International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430
- Conditions
- Hyponatremia With Normal Extracellular Fluid VolumeHyponatremia With Excess Extracellular Fluid Volume
- First Posted Date
- 2010-01-26
- Last Posted Date
- 2011-06-21
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 135
- Registration Number
- NCT01056848
- Locations
- 🇺🇸
Innovative Research of West Florida, Clearewater, Florida, United States
🇺🇸Torrance Clinical Research, Lomita, California, United States
🇺🇸Fleming Island Center for Clinical Research, Fleming Island, Florida, United States
Study to Evaluate the Effects of Oral Administration of Lixivaptan in Patients With Congestive Heart Failure
- First Posted Date
- 2010-01-26
- Last Posted Date
- 2011-06-28
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 170
- Registration Number
- NCT01055912
- Locations
- 🇺🇸
Innovative Research of West Florida, Inc, Clearwater, Florida, United States
🇺🇸Charlotte Heart Group Research Center, Port Charlotte, Florida, United States
🇺🇸Capitol Interventional Cardiology, Carmichael, California, United States
International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
- First Posted Date
- 2009-04-07
- Last Posted Date
- 2010-11-23
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 300
- Registration Number
- NCT00876876
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia
- First Posted Date
- 2009-04-07
- Last Posted Date
- 2011-06-28
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 206
- Registration Number
- NCT00876798
- Locations
- 🇺🇸
Innovative Research of West Florida, Inc., Clearwater, Florida, United States
🇺🇸Galiz Research, Miami, Florida, United States
🇺🇸Miami Jewish Home and Hospital for the Aged, Miami, Florida, United States
A Study to Define the ECG Effects of Lixivaptan Compared to Placebo and Moxifloxacin in Healthy Adult Men and Women: A Thorough ECG Study
- First Posted Date
- 2008-05-12
- Last Posted Date
- 2011-06-21
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 298
- Registration Number
- NCT00675701
- Locations
- 🇺🇸
Research Site 1, Austin, Texas, United States
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia
- Conditions
- Hyponatremia With Normal Extracellular Fluid Volume
- Interventions
- Drug: placebo
- First Posted Date
- 2008-04-18
- Last Posted Date
- 2011-06-28
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 106
- Registration Number
- NCT00660959
- Locations
- 🇮🇳
Poona Hospital and Research Centre, Pune, Maharashtra, India
🇺🇸RTR Medical Group, Savannah, Georgia, United States
🇺🇸Four Rivers Clinical Research, Inc., Paducah, Kentucky, United States
THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation
- First Posted Date
- 2007-12-21
- Last Posted Date
- 2011-06-28
- Lead Sponsor
- CardioKine Inc.
- Target Recruit Count
- 652
- Registration Number
- NCT00578695
- Locations
- 🇵🇱
Samodzielny Publiczny Zaklad Opieki Zdrowotnej, Sieradz, Poland
🇮🇳Shree Saibaba Heart Institute and Research Centre, Shalimar, Nashik, India
🇵🇱Research Site 2, Krakow, Poland