UNIVERSITY OF CALIFORNIA, IRVINE

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private, Subsidiary

Established: 1965-01-01

Employees: 10K

Market Cap: -

Website: http://www.uci.edu

Clinical Trials

A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors

Not Applicable

Recruiting

Conditions: Testicular Cancer

Interventions: Behavioral: Individual Supportive Listening
Behavioral: Goal-Focused Emotion-Regulation Therapy (GET)

First Posted Date: 2023-05-01

Last Posted Date: 2024-04-03

Lead Sponsor: University of California, Irvine

Target Recruit Count: 250

Registration Number: NCT05836688

Locations: 🇺🇸
University of California, Irvine, Irvine, California, United States

Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures

Not Applicable

Recruiting

Conditions: Surgery
Anesthesia, Local
Fasting

Interventions: Other: Fasting
Other: Non-fasting

First Posted Date: 2023-04-19

Last Posted Date: 2024-08-26

Lead Sponsor: University of California, Irvine

Target Recruit Count: 134

Registration Number: NCT05819801

Locations: 🇺🇸
UCI Health Manchester Pavilion, Orange, California, United States

Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Patients

Not Applicable

Conditions: Depression, Anxiety

Interventions: Behavioral: Supported dCBT
Behavioral: Unsupported dCBT

First Posted Date: 2023-02-28

Last Posted Date: 2024-05-09

Lead Sponsor: University of California, Irvine

Target Recruit Count: 426

Registration Number: NCT05746767

Locations: 🇺🇸
University of California, Irvine, California, United States
🇺🇸
Zuckerberg San Francisco General, San Francisco, California, United States

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

Phase 1

Not yet recruiting

Conditions: Gastroesophageal Adenocarcinoma

Interventions: Device: ctDNA Blood Test
Combination Product: FLOT
Combination Product: FOLFOX
Combination Product: FOLFIRI
Combination Product: FOLFIRINOX
Combination Product: PACLITAXEL with or without CARBOPLATIN
Combination Product: DOCETAXEL and IRINOTECAN (alone or combined)
Drug: NIVOLUMAB (alone or when added to a regimen above)
Drug: PEMBROLIZUMAB (alone or when added to a regimen above)

First Posted Date: 2023-02-17

Last Posted Date: 2024-02-28

Lead Sponsor: University of California, Irvine

Target Recruit Count: 20

Registration Number: NCT05733689

Locations: 🇺🇸
Chao Family Comprehensive Cancer Center, University, Orange, California, United States

SSIs for Mental Health and Loneliness

Not Applicable

Completed

Conditions: Loneliness
Mental Health Issue
Anxiety
Distress, Emotional
Stress
Depression

Interventions: Behavioral: Overcoming Loneliness single-session intervention
Behavioral: Single-session "Sharing Feelings" program
Behavioral: Overcoming Loneliness three-week intervention
Behavioral: The Action Brings Change (ABC) Program (TEAM Lab version)
Behavioral: Online help-seeking as usual
Behavioral: Overcoming loneliness SSI 8-minute version

First Posted Date: 2023-01-18

Last Posted Date: 2024-07-22

Lead Sponsor: University of California, Irvine

Target Recruit Count: 4370

Registration Number: NCT05687162

Locations: 🇺🇸
Online (based at UC Irvine), Irvine, California, United States

Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures

Not Applicable

Completed

Conditions: Blood Pressure
Dietary Habits
Blood Sugar; High

Interventions: Other: Regular sweetened commercial foods
Other: Whole and minimally processed and sweetened foods
Other: Allulose sweetened commercial foods

First Posted Date: 2022-12-21

Last Posted Date: 2023-05-03

Lead Sponsor: University of California, Irvine

Target Recruit Count: 15

Registration Number: NCT05658757

Locations: 🇺🇸
University of California, Irvine, Irvine, California, United States

Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County

Not Applicable

Active, not recruiting

Conditions: Hypertension

Interventions: Behavioral: Enhanced Standard Intervention
Behavioral: SERVE OC Intervention

First Posted Date: 2022-12-07

Last Posted Date: 2024-08-07

Lead Sponsor: University of California, Irvine

Target Recruit Count: 483

Registration Number: NCT05641519

Locations: 🇺🇸
University of California, Irvine, Irvine, California, United States

Effects of Mouthrinses on the Microbiome of the Oral Cavity and GI Tract

Not Applicable

Recruiting

Conditions: Microbial Colonization
Viral Infection
Oral Bacterial Infection
Oral Infection

Interventions: Other: Lumineux Oral Essentials rinse
Other: Listerine rinse

First Posted Date: 2022-11-03

Last Posted Date: 2024-04-03

Lead Sponsor: University of California, Irvine

Target Recruit Count: 200

Registration Number: NCT05603650

Locations: 🇺🇸
Beckman Laser Institute and Medical Clinic, Irvine, California, United States

De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

Recruiting

Conditions: HPV Positive Oropharyngeal Squamous Cell Carcinoma

Interventions: Radiation: Intensity-Modulated Radiation Therapy (IMRT)

First Posted Date: 2022-11-01

Last Posted Date: 2024-04-26

Lead Sponsor: University of California, Irvine

Target Recruit Count: 111

Registration Number: NCT05600842

Locations: 🇺🇸
Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California, United States

Decolonization to Reduce After-Surgery Events of Surgical Site Infection

Phase 4

Recruiting

Conditions: Surgical Site Infection

Interventions: Drug: Soap Without Antiseptic Properties (Placebo)
Drug: 4% Chlorhexidine Gluconate
Drug: 2% Mupirocin
Drug: Placebo Nasal Ointment

First Posted Date: 2022-10-19

Last Posted Date: 2024-08-26

Lead Sponsor: University of California, Irvine

Target Recruit Count: 2700

Registration Number: NCT05586776

Locations: 🇺🇸
Hoag Memorial Hospital Presbyterian, Newport Beach, California, United States
🇺🇸
University of California, San Francisco Medical Center, San Francisco, California, United States
🇺🇸
University of California, Irvine Medical Center, Orange, California, United States

and more 1 locations

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