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Merck, Inc.

Merck, Inc. logo
🇺🇸United States
Ownership
Subsidiary
Employees
-
Market Cap
$295.3B
Website
http://www.merck.ph

Efficacy and Tolerability Study of V501 in Japanese Males (V501-122)

Phase 3
Completed
Conditions
Condyloma Acuminata
Anogenital Human Papilloma Virus Infection
Interventions
Biological: Placebo
Biological: V501
First Posted Date
2013-05-27
Last Posted Date
2019-04-02
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
1124
Registration Number
NCT01862874

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022)

Phase 3
Completed
Conditions
Hypercholesterolemia
Interventions
Drug: Placebo
First Posted Date
2013-05-23
Last Posted Date
2020-05-29
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
589
Registration Number
NCT01860729

MK-8237 (SCH900237) Biomarker Study in Participants With Allergic Rhinitis or Rhinoconjunctivitis (MK-8237-009)

Phase 1
Completed
Conditions
Allergic Rhinoconjunctivitis
Allergic Rhinitis
Interventions
Biological: MK-8237
Biological: NAC
Other: Placebo
First Posted Date
2013-05-14
Last Posted Date
2019-03-15
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
26
Registration Number
NCT01852825

Samatasvir (IDX719) in Combinations With Simeprevir and/or TMC647055/Ritonavir With or Without Ribavirin for 12 Weeks in Participants With Chronic Hepatitis C Infection (MK-1894-005)

Phase 2
Completed
Conditions
Chronic Hepatitis C Virus
Interventions
Biological: Pegylated interferon (Peg-IFN)
Other: Samatasvir matching placebo
First Posted Date
2013-05-14
Last Posted Date
2015-04-23
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
143
Registration Number
NCT01852604

Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012)

Phase 2
Terminated
Conditions
Alzheimer's Disease
Interventions
Drug: Placebo
Drug: AChEI
First Posted Date
2013-05-13
Last Posted Date
2018-09-18
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
240
Registration Number
NCT01852110

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-012/KEYNOTE-012)

Phase 1
Completed
Conditions
Cancer
Solid Tumor
Interventions
Biological: Pembrolizumab
First Posted Date
2013-05-08
Last Posted Date
2021-06-28
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
297
Registration Number
NCT01848834

Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)

Phase 3
Terminated
Conditions
Homozygous Familial Hypercholesterolemia
Hyperlipoproteinemia Type II
Interventions
Drug: Placebo
First Posted Date
2013-04-26
Last Posted Date
2015-06-01
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
2
Registration Number
NCT01841684

Study of Pembrolizumab (MK-3475) Monotherapy in Advanced Solid Tumors and Pembrolizumab Combination Therapy in Advanced Non-small Cell Lung Cancer/ Extensive-disease Small Cell Lung Cancer (MK-3475-011/KEYNOTE-011)

Phase 1
Completed
Conditions
Solid Tumor
Non-small Cell Lung Cancer
Small Cell Lung Cancer
Interventions
Biological: Pembrolizumab 2 mg/kg
Biological: Pembrolizumab 10 mg/kg
Biological: Pembrolizumab 200 mg
Biological: Ipilimumab 1 mg/kg
Drug: Nab-paclitaxel 100 mg/m^2
First Posted Date
2013-04-25
Last Posted Date
2021-06-22
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
57
Registration Number
NCT01840579

The Pharmacokinetics of MK-7145 Following Single Dose Administration in Participants With Moderate Renal Insufficiency (MK-7145-018)

Phase 1
Withdrawn
Conditions
Renal Insufficiency
Interventions
First Posted Date
2013-04-15
Last Posted Date
2013-09-24
Lead Sponsor
Merck Sharp & Dohme LLC
Registration Number
NCT01832103
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