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International Partnership for Microbicides, Inc.

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

A Safety and Pharmacokinetic Study for Dapivirine and Maraviroc Gel in Belgium

Phase 1

Withdrawn

Conditions: HIV Infections

Interventions: Drug: Maraviroc Vaginal Gel
Drug: Dapivirine Vaginal Gel
Drug: Matching Placebo Gel
Drug: Maraviroc/Dapivirine Gel

First Posted Date: 2010-11-17

Last Posted Date: 2011-09-09

Lead Sponsor: International Partnership for Microbicides, Inc.

Registration Number: NCT01242579

A Safety Study to Assess the Delivery of Dapivirine From a Matrix Vaginal Ring

Phase 1

Completed

Conditions: HIV Infections

Interventions: Drug: dapivirine
Drug: placebo

First Posted Date: 2010-06-15

Last Posted Date: 2010-10-06

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 45

Registration Number: NCT01144676

Locations: 🇧🇪
SGS Life Science Services, Antwerp, Flanders, Belgium

A Safety Study of Dapivirine Vaginal Ring in Africa

Phase 1

Completed

Conditions: HIV Infections

First Posted Date: 2010-02-19

Last Posted Date: 2011-08-02

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 280

Registration Number: NCT01071174

Locations: 🇰🇪
Kenya Medical Research Institute (KEMRI), Kisumu, Kenya
🇲🇼
University of North Carolina Project, Lilongwe, Malawi
🇿🇦
Reproductive Health and HIV Research Unit (RHRU), Edendale, Kwazulu Natal, South Africa

and more 7 locations

An Expanded Safety Study of Dapivirine Gel 4759 in Africa

Phase 1

Completed

Conditions: HIV Infections
Acquired Immunodeficiency Syndrome

Interventions: Drug: placebo
Drug: dapivirine

First Posted Date: 2009-06-10

Last Posted Date: 2011-09-12

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 280

Registration Number: NCT00917891

Locations: 🇰🇪
Kenya Medical Research Institute, Kisumu, Kenya
🇲🇼
Johns Hopkins Project, College of Medicine, Blantyre, Malawi
🇷🇼
Projet Ubuzima, Kigali, Rwanda

and more 7 locations

An Expanded Safety Study of Dapivirine Gel 4789 in Africa

Phase 1

Completed

Conditions: HIV Infections
Acquired Immunodeficiency Syndrome
Healthy

Interventions: Drug: placebo
Drug: dapivirine

First Posted Date: 2009-06-10

Last Posted Date: 2011-12-14

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 100

Registration Number: NCT00917904

Locations: 🇿🇦
Be Part Clinic, Mbekweni, Paarl, Eastern Cape, South Africa
🇿🇦
Madibeng Centre for Research, Brits, North West Province, South Africa
🇿🇦
Desmond Tutu HIV Foundation, Masiphumelele, Cape Town, Western Cape, South Africa

A Safety Study of Two Dapivirine (TMC120) Vaginal Gels in the United States

Phase 1

Completed

Conditions: HIV-1 Infections

Interventions: Drug: dapivirine gel 4759
Drug: dapivirine 4789
Drug: Drug placebo

First Posted Date: 2008-11-27

Last Posted Date: 2022-10-25

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 128

Registration Number: NCT00799058

Locations: 🇺🇸
University of Alabama at Birmingham, Alabama Microbicide Clinical Research Site (AMCRS), Birmingham, Alabama, United States
🇺🇸
Harbor-UCLA Medical Center, Torrance, California, United States
🇺🇸
University of Illinois at Chicago, Chicago, Illinois, United States

and more 2 locations

Feasibility Study of a Vaginal Ring for Delivery of TMC120 (Dapivirine)

Phase 1

Completed

Conditions: HIV Infections

Interventions: Drug: placebo vaginal ring
Drug: TMC120 (dapivirine) vaginal ring

First Posted Date: 2008-06-18

Last Posted Date: 2009-09-01

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 12

Registration Number: NCT00700284

Locations: 🇧🇪
Drug Research Unit, UZ Gent, Gent, Belgium

A Phase I Pharmacokinetics and Safety Study of Two Dapivirine Intravaginal Gels

Phase 1

Completed

Conditions: HIV Infections

Interventions: Drug: Dapivirine Gel 4750, 0.05%, 2.5g
Drug: Dapivirine Gel 4789, 0.05%, 2.5g
Drug: HEC-based Placebo Gel

First Posted Date: 2008-02-13

Last Posted Date: 2009-03-27

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 36

Registration Number: NCT00613249

Locations: 🇧🇪
SGS Life Science Services Research Unit Stuivenberg, Antwerp, Belgium

A Safety and Acceptability Study of a Vaginal Ring Microbicide Delivery Method

Early Phase 1

Completed

Conditions: HIV Infections

First Posted Date: 2007-05-04

Last Posted Date: 2010-11-15

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 220

Registration Number: NCT00469170

Locations: 🇿🇦
Reproductive Health & HIV Research Unit - Sheshisani IPM Clinic, Yeoville, Johannesburg, South Africa
🇿🇦
South African Medical Research Council, Durban, KwaZulu Natal, South Africa
🇿🇦
Desmond Tutu HIV Foundation, Masiphumelele, Cape Town, South Africa

and more 1 locations

A Pharmacokinetic Study of Dapivirine Vaginal Rings in Belgium

Phase 1

Completed

Conditions: HIV Infections

Interventions: Other: placebo intravaginal ring
Drug: dapivirine reservoir intravaginal ring
Drug: dapivirine matrix intravaginal ring

First Posted Date: 2007-05-04

Last Posted Date: 2009-09-01

Lead Sponsor: International Partnership for Microbicides, Inc.

Target Recruit Count: 24

Registration Number: NCT00469768

Locations: 🇧🇪
Drug Research Unit Ghent (D.R.U.G.), Ghent, Belgium

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