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Cellectar BioSciences

๐Ÿ‡บ๐Ÿ‡ธUnited States
Ownership
Public
Employees
20
Market Cap
-
Website
http://www.cellectar.com
Introduction

Cellectar Biosciences, Inc. engages in the development of phospholipid drug conjugates (PDCs) for the treatment and imaging of cancer. Its portfolio includes CLR 131, which seeks to treat relapse or refractory multiple myeloma, CLR 125, which intends to treat micro metastatic disease, CLR 124 which could detect tumors and metastases in a broad range of cancers and CLR 1502, a cancer-targeting near-infrared-fluorophore optical imaging PDC for intraoperative tumor and tumor margin illumination. The company was founded in June 1996 and is headquartered in Florham Park, NJ.

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

Phase 1
Recruiting
Conditions
High-Grade Glioma
Interventions
Drug: CLR 131
First Posted Date
2022-11-09
Last Posted Date
2024-07-08
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
50
Registration Number
NCT05610891
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Wisconsin, Carbone Cancer Center, Madison, Wisconsin, United States

๐Ÿ‡จ๐Ÿ‡ฆ

Hospital for Sick Children, Toronto, Ontario, Canada

๐Ÿ‡บ๐Ÿ‡ธ

Stanford University, Palo Alto, California, United States

and more 5 locations

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma

Phase 1
Active, not recruiting
Conditions
DIPG
Neuroblastoma
Ewing Sarcoma
Pediatric Solid Tumor
Pediatric Brain Tumor
Rhabdomyosarcoma
Osteosarcoma
Pediatric Lymphoma
Interventions
Drug: CLR 131
First Posted Date
2018-03-27
Last Posted Date
2023-05-17
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
30
Registration Number
NCT03478462
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Texas Children's Hospital, Houston, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Memorial Sloan Kettering Cancer Center, New York, New York, United States

๐Ÿ‡ฆ๐Ÿ‡บ

Children's Hospital at Westmead, Westmead, New South Wales, Australia

and more 5 locations

Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia

Phase 2
Recruiting
Conditions
Small Lymphocytic Lymphoma
Lymphoplasmacytic Lymphoma
Waldenstrom Macroglobulinemia
Multiple Myeloma
Marginal Zone Lymphoma
Diffuse Large B Cell Lymphoma
Chronic Lymphocytic Leukemia
Mantle Cell Lymphoma
Central Nervous System Lymphoma
Interventions
Drug: Iopofosine I 131 single dose
Drug: Iopofosine I 131 multiple dose
Drug: Iopofosine I 131 fractionated dose
First Posted Date
2016-11-02
Last Posted Date
2024-06-06
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
120
Registration Number
NCT02952508
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Cellectar Biosciences site, London, United Kingdom

๐Ÿ‡น๐Ÿ‡ท

Cellectar Biosciences, Istanbul, Turkey

๐Ÿ‡ฎ๐Ÿ‡ฑ

Cellectar Biosciences Site, Jerusalem, Israel

Dose Escalation Study of I-131-CLR1404 in Patients With Relapsed or Refractory Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2014-10-30
Last Posted Date
2023-02-22
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
31
Registration Number
NCT02278315
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

๐Ÿ‡บ๐Ÿ‡ธ

Mayo Clinic, Jacksonville, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Loyola University Medical Center, Maywood, Illinois, United States

and more 1 locations

Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma

Phase 2
Terminated
Conditions
Glioblastoma
Interventions
Drug: I-124-CLR1404
First Posted Date
2013-07-12
Last Posted Date
2015-09-09
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
7
Registration Number
NCT01898273
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Ohio State University Medical Center, Columbus, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

City of Hope, Duarte, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

and more 6 locations

Open-Label Study of I-131-CLR1404 in Subjects With Recurrent Glioma

Phase 2
Withdrawn
Conditions
Glioma
Interventions
First Posted Date
2013-01-29
Last Posted Date
2014-02-25
Lead Sponsor
Cellectar Biosciences, Inc.
Registration Number
NCT01778088
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Maryland School of Medicine, Baltimore, Maryland, United States

Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned

Phase 1
Completed
Conditions
Cancer
Interventions
First Posted Date
2011-12-20
Last Posted Date
2015-02-26
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
12
Registration Number
NCT01495663
Locations
๐Ÿ‡บ๐Ÿ‡ธ

City of Hope National Medical Center, Duarte, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

๐Ÿ‡บ๐Ÿ‡ธ

Georgetown University Hospital, Washington, DC, District of Columbia, United States

A Trial of NOV-205 in Hepatitis C Patients Who Failed Standard Therapy

Phase 2
Completed
Conditions
Hepatitis C
Interventions
Drug: NOV-205
First Posted Date
2010-01-28
Last Posted Date
2022-07-25
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
22
Registration Number
NCT01058512
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Orlando Immunology Center, Orlando, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

UMASS Memorial Medical Center, Worcester, Massachusetts, United States

๐Ÿ‡บ๐Ÿ‡ธ

MetroWest Medical Center, Framingham, Massachusetts, United States

and more 3 locations

Safety and PK Study of NOV-205 to Treat Chronic HCV Who Fail Standard Therapy

Phase 1
Completed
Conditions
Hepatitis C
First Posted Date
2006-09-07
Last Posted Date
2007-12-21
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
30
Registration Number
NCT00372983

Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer

Phase 3
Completed
Conditions
Non Small Cell Lung Cancer
Interventions
First Posted Date
2006-07-04
Last Posted Date
2022-07-25
Lead Sponsor
Cellectar Biosciences, Inc.
Target Recruit Count
903
Registration Number
NCT00347412
Locations
๐Ÿ‡ต๐Ÿ‡ฑ

Oddzial Chemioterapii Zaklad Opieki Zdrowotnej MSWiA, Olsztyn, Poland

๐Ÿ‡ต๐Ÿ‡ฑ

Oddzial Gruzlicy I Chorob Pluc I P, Prabuty, Poland

๐Ÿ‡ท๐Ÿ‡ด

Institute of Oncology, Department of Medical Oncology II, Bucharest, Romania

and more 72 locations
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