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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

Clinical Trials

1.7k

Active:133
Completed:1209

Trial Phases

6 Phases

Early Phase 1:1
Phase 1:573
Phase 2:352
+3 more phases

Drug Approvals

11

SFDA:10
CIMA_AEMPS:1

Drug Approvals

REVIA COMPRIMIDOS RECUBIERTOS

Approval Date
Jul 14, 2025
CIMA_AEMPS

Clinical Trials

Distribution across different clinical trial phases (1339 trials with phase data)• Click on a phase to view related trials

Phase 1
573 (42.8%)
Phase 2
352 (26.3%)
Phase 3
320 (23.9%)
Phase 4
53 (4.0%)
Not Applicable
37 (2.8%)
phase_1_2
2 (0.1%)
Early Phase 1
1 (0.1%)
phase_2_3
1 (0.1%)

A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East

Not yet recruiting
Conditions
β-thalassemia
Interventions
First Posted Date
2025-10-14
Last Posted Date
2025-10-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
200
Registration Number
NCT07215975
Locations
🇸🇦

Prince Muhammad bin Nasser Hospital, Jizan, Saudi Arabia

Long-Term Safety Outcomes and First-Line Treatment Patterns in Patients With Non-Small Cell Lung Cancer and Programmed Death-1 (Pd-L1) <1%

Active, not recruiting
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
Biological: Nivolumab + ipilimumab + platinum-based chemotherapy
Biological: Immuno-oncology-based therapy (excluding nivolumab-based regimens) with chemotherapy
Biological: Other dual-immuno-oncology therapy with chemotherapy
First Posted Date
2025-10-14
Last Posted Date
2025-10-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
300
Registration Number
NCT07215962
Locations
🇺🇸

Florida Cancer Specialists & Research Institute, Fleming Island, Florida, United States

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

Not Applicable
Not yet recruiting
Conditions
Renal Cell Carcinoma
Interventions
Drug: BMS-986506
First Posted Date
2025-09-29
Last Posted Date
2025-10-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
125
Registration Number
NCT07195682
Locations
🇺🇸

Local Institution - 0029, New York, New York, United States

🇺🇸

Local Institution - 0006, Boston, Massachusetts, United States

🇺🇸

Local Institution - 0002, Philadelphia, Pennsylvania, United States

and more 6 locations

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

Not yet recruiting
Conditions
Systemic Lupus Erythematosus (SLE)
Interventions
Drug: Current standard of care treatment options
First Posted Date
2025-09-16
Last Posted Date
2025-09-16
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
223
Registration Number
NCT07175285
Locations
🇺🇸

Local Institution - 0035, San Diego, California, United States

🇺🇸

Local Institution - 0034, Ann Arbor, Michigan, United States

🇺🇸

Local Institution - 0039, Brooklyn, New York, United States

and more 8 locations

A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis

Not Applicable
Not yet recruiting
Conditions
Rheumatoid Arthritis
Interventions
Other: Placebo
First Posted Date
2025-09-15
Last Posted Date
2025-09-15
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
46
Registration Number
NCT07171983
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News

Takeda Expands AI Drug Discovery Partnership with Nabla Bio in $1B+ Deal

Takeda Pharmaceutical has signed a second multi-year AI partnership with Nabla Bio, potentially worth over $1 billion including milestone payments, to accelerate early-stage drug discovery using artificial intelligence.

iMDx Appoints Marketing VP to Spearhead Commercial Launch of Transplant Rejection Diagnostic

Insight Molecular Diagnostics (iMDx) has appointed Steven Tahmooressi as Vice President of Marketing to lead the commercial launch of its GraftAssureDx transplant rejection diagnostic kit.

Bristol Myers Squibb and Lilly Showcase Major Oncology Data at ESMO 2025

Bristol Myers Squibb will present data from over 50 studies at ESMO 2025, including first-in-class results from izalontamab brengitecan (iza-bren), an EGFRxHER3 bispecific ADC that received FDA Breakthrough Therapy designation for EGFR-mutated NSCLC.

Eli Lilly and AstraZeneca Emerge as Leading Candidates for Next Trump Administration Drug Pricing Deal

Wall Street analysts predict Eli Lilly and AstraZeneca are the most likely pharmaceutical companies to strike the next drug pricing deal with the Trump administration following Pfizer's September 29 agreement.

Bristol Myers Squibb Acquires Orbital Therapeutics for $1.5 Billion to Advance In Vivo CAR-T Cell Therapy

Bristol Myers Squibb announced the acquisition of private startup Orbital Therapeutics for $1.5 billion in cash to strengthen its cell therapy portfolio.

Halozyme Acquires Elektrofi for $750M to Expand Ultra-High Concentration Drug Delivery Technology

Halozyme Therapeutics has agreed to acquire Elektrofi for $750 million upfront plus up to $150 million in milestone payments, gaining access to breakthrough Hypercon microparticle technology.

Bristol Myers Squibb's Anti-Tau Antibody BMS-986446 Receives FDA Fast Track Designation for Alzheimer's Disease

The FDA has granted Fast Track Designation to BMS-986446, Bristol Myers Squibb's anti-microtubule binding region-tau antibody currently in Phase 2 development for early Alzheimer's disease.

Major Pharma Companies Form AI Consortium to Accelerate Drug Discovery Through Federated Data Sharing

Bristol Myers Squibb, Takeda Pharmaceuticals, and Astex Pharmaceuticals are joining an AI consortium with AbbVie and Johnson & Johnson to train the OpenFold3 drug discovery model.

FDA Halts New Drug Application Acceptance as Government Shutdown Begins

The FDA will not accept new drug applications during the government shutdown, though it can continue reviewing existing submissions funded by user fees.

Revolution Medicines Appoints Alan Sandler as Chief Development Officer to Advance RAS-Targeted Cancer Pipeline

Revolution Medicines has appointed Alan Sandler, M.D. as chief development officer to lead development of RAS(ON) inhibitors for RAS-addicted cancers.

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