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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)

Phase 2
Terminated
Conditions
Nonalcoholic Steatohepatitis (NASH)
Interventions
Other: Placebo
First Posted Date
2020-02-12
Last Posted Date
2024-02-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
124
Registration Number
NCT04267393
Locations
🇺🇸

Local Institution - 0150, Baltimore, Maryland, United States

🇺🇸

Local Institution - 0171, Dallas, Texas, United States

🇺🇸

Local Institution - 0143, Redwood City, California, United States

and more 99 locations

A Study to Examine the Acceptable Taste and to Estimate the Amount of Atazanavir and Cobicistat in the Body When Taken as a Combination Product Versus When Taken as Separate Products at the Same Time

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: Atazanavir/Cobicistat
First Posted Date
2020-02-10
Last Posted Date
2021-11-23
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
34
Registration Number
NCT04263350
Locations
🇺🇸

PPD Development, LP, Austin, Texas, United States

Pharmacokinetics (Drug Levels in Blood) of BMS-986165 When Taken as Various Solid Tablet Prototypes by Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Drug: BMS-986165 prototype 2
Drug: BMS-986165 prototype 1
First Posted Date
2020-01-30
Last Posted Date
2020-04-09
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
18
Registration Number
NCT04249284
Locations
🇺🇸

Quotient Sciences Miami, Miami, Florida, United States

A Study to Evaluate the Pharmacokinetics (Drug Levels and Metabolism), Safety, and Tolerability of BMS-986259 in Participants With Various Levels of Kidney Function

Phase 1
Completed
Conditions
Renal Failure
Interventions
First Posted Date
2020-01-23
Last Posted Date
2021-09-24
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
30
Registration Number
NCT04237831
Locations
🇺🇸

Clinical Pharmacology of Miami, Miami, Florida, United States

🇺🇸

Orlando Clinical Research Center, Orlando, Florida, United States

🇺🇸

Prism Clinical Research, Saint Paul, Minnesota, United States

A Single-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-986263 in Participants With Varying Degrees of Liver Impairment

Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
First Posted Date
2020-01-13
Last Posted Date
2021-11-05
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
40
Registration Number
NCT04225936
Locations
🇺🇸

The Texas Liver Institute, San Antonio, Texas, United States

A Study Comparing the Effects of Famotidine Pretreatment and of Food on the Relative Bioavailability of BMS-986165 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2019-12-24
Last Posted Date
2020-04-21
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
18
Registration Number
NCT04209699
Locations
🇺🇸

PRA Health Sciences - Salt Lake, Salt Lake City, Utah, United States

A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer

Phase 3
Completed
Conditions
Bladder Tumor
Muscle-Invasive Bladder Cancer
Bladder Cancer
Interventions
Biological: Nivolumab
Procedure: Radical cystectomy (RC)
Biological: Bempegaldesleukin
First Posted Date
2019-12-23
Last Posted Date
2024-06-27
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
114
Registration Number
NCT04209114
Locations
🇩🇪

Local Institution - 0117, Duesseldorf, Germany

🇨🇦

Local Institution - 0036, Sherbrooke, Quebec, Canada

🇨🇦

Local Institution - 0082, Oshawa, Ontario, Canada

and more 103 locations

A Retrospective Observational Study on the Long-term Effects of Ipilimumab-treated Pediatric Participants in the Dutch Melanoma Treatment Registry (DMTR)

Active, not recruiting
Conditions
Melanoma
Interventions
First Posted Date
2019-12-12
Last Posted Date
2019-12-12
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
10
Registration Number
NCT04196452
Locations
🇺🇸

Local Institution, Princeton, New Jersey, United States

Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Phase 2
Completed
Conditions
Autoimmune Disorder
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Primary Sjögren's Syndrome
Interventions
First Posted Date
2019-12-05
Last Posted Date
2024-01-16
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
119
Registration Number
NCT04186871
Locations
🇺🇸

Local Institution - 0083, Spokane, Washington, United States

🇺🇸

Local Institution - 0024, Encino, California, United States

🇫🇷

Local Institution - 0075, Brest, France

and more 71 locations

A Study Assessing the Drug Levels, Drug Effects, and Safety of BMS-986322 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
Other: BMS-986322 Placebo
First Posted Date
2019-11-25
Last Posted Date
2022-05-31
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
171
Registration Number
NCT04175925
Locations
🇺🇸

ICON (LPRA) - Lenexa, Lenexa, Kansas, United States

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