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BRISTOL MYERS SQUIBB

🇫🇷France
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

First Posted Date
2019-07-05
Last Posted Date
2024-12-18
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
1147
Registration Number
NCT04008030
Locations
🇩🇪

Local Institution - 0117, Hamburg, Germany

🇩🇪

Local Institution - 0008, Hannover, Germany

🇩🇪

Local Institution - 0009, Heidelberg, Germany

and more 159 locations

An Investigational Immunotherapy Study of BMS-986288 Alone and in Combination With Nivolumab in Advanced Solid Cancers

Phase 1
Completed
Conditions
Advanced Cancer
Interventions
First Posted Date
2019-06-21
Last Posted Date
2024-10-07
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
219
Registration Number
NCT03994601
Locations
🇺🇸

Local Institution - 0075, Costa Mesa, California, United States

🇺🇸

Local Institution - 0050, Orange, California, United States

🇪🇸

Local Institution - 0024, Majadahonda, Spain

and more 37 locations

A Study of the Pharmacokinetic Interaction Between Pirfenidone and BMS-986278 in Healthy Participants

Phase 1
Completed
Conditions
Idiopathic Pulmonary Fibrosis (IPF)
Interventions
First Posted Date
2019-06-10
Last Posted Date
2020-05-15
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
22
Registration Number
NCT03981094
Locations
🇺🇸

PRA Health Sciences - Salt Lake, Salt Lake City, Utah, United States

A Study to Compare Nivolumab Drug Product Process D to Nivolumab Drug Product Process C in Participants With Stage IIIa/b/c/d or Stage IV Melanoma After Complete Resection

Phase 1
Completed
Conditions
Melanoma
Interventions
First Posted Date
2019-06-10
Last Posted Date
2023-12-15
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
261
Registration Number
NCT03980314
Locations
🇺🇸

Local Institution - 0043, Pittsburgh, Pennsylvania, United States

🇧🇷

Local Institution - 0039, Barretos, Sao Paulo, Brazil

🇧🇷

Local Institution - 0041, Rio de Janeiro, Brazil

and more 34 locations

A Study to Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment

Phase 1
Terminated
Conditions
Melanoma
Interventions
First Posted Date
2019-06-07
Last Posted Date
2024-07-24
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
11
Registration Number
NCT03978611
Locations
🇺🇸

Local Institution - 0002, Los Angeles, California, United States

🇧🇪

Local Institution - 0018, Bruxelles, Brussels, Belgium

🇧🇪

Local Institution - 0016, Brussels, Belgium

and more 25 locations

A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: BMS-986165
Drug: Rabeprazole
First Posted Date
2019-06-07
Last Posted Date
2020-11-02
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
21
Registration Number
NCT03979248
Locations
🇳🇱

PRA Health Sciences - Netherlands, Groningen, Netherlands

Single and Multiple Dose Pharmacokinetics of BMS-986165 in a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Chinese Subjects

Phase 1
Completed
Conditions
Autoimmune Diseases
Interventions
Drug: BMS-986165
Other: Placebo
First Posted Date
2019-05-21
Last Posted Date
2020-06-18
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
135
Registration Number
NCT03956953
Locations
🇨🇳

Local Institution, Beijing, Beijing, China

An Investigational Immunotherapy Study of BMS-986301 Alone or in Combination With Nivolumab, and Ipilimumab in Participants With Advanced Solid Cancers

Phase 1
Completed
Conditions
Advanced Solid Cancers
Interventions
Drug: BMS-986301
Biological: Nivolumab
Biological: Ipilimumab
First Posted Date
2019-05-21
Last Posted Date
2024-05-20
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
54
Registration Number
NCT03956680
Locations
🇺🇸

Local Institution - 0003, Chicago, Illinois, United States

🇺🇸

Local Institution - 0002, Nashville, Tennessee, United States

🇺🇸

Local Institution - 0005, Saint Louis, Missouri, United States

and more 2 locations

A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of BMS-986256 in Healthy Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2019-05-15
Last Posted Date
2020-02-25
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
15
Registration Number
NCT03950960
Locations
🇺🇸

PRA Health Sciences - Lenexa, Lenexa, Kansas, United States

An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis

Phase 2
Terminated
Conditions
Lupus Nephritis
Interventions
Drug: BMS-986165
Drug: Placebo
Drug: Mycophenolate Mofetil
First Posted Date
2019-05-09
Last Posted Date
2022-10-17
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
16
Registration Number
NCT03943147
Locations
🇺🇸

The Regents of The University of California, Los Angeles, California, United States

🇺🇸

NewYork-Presbyterian Queens, Fresh Meadows, New York, United States

🇺🇸

Northwell Health Physician Partners at Great Neck, Great Neck, New York, United States

and more 84 locations
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