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BRISTOL MYERS SQUIBB

🇫🇷France
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: BMS-986205
First Posted Date
2017-12-05
Last Posted Date
2018-02-23
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
40
Registration Number
NCT03362411
Locations
🇺🇸

PPD Austin Clinic, Austin, Texas, United States

A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function

Phase 2
Completed
Conditions
Heart Failure
Cardiac Failure
Reduced Ventricular Ejection Fraction
Interventions
Drug: HNO Donor
Drug: Nitroglycerin (NTG)
Other: Placebo
First Posted Date
2017-11-30
Last Posted Date
2020-07-27
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
49
Registration Number
NCT03357731
Locations
🇺🇸

Orange County Research Center, Tustin, California, United States

🇺🇸

Brigham and Womens Hospital, Boston, Massachusetts, United States

🇺🇸

Inova Heart and Vascular Institute, Falls Church, Virginia, United States

and more 4 locations

An Investigational Immuno-Therapy Study of Experimental Medication BMS-986242 Given in Combination With Nivolumab in Patients With Advanced Cancer

Phase 1
Terminated
Conditions
Cancer
Interventions
Drug: BMS-986242
Biological: Nivolumab
First Posted Date
2017-11-22
Last Posted Date
2020-08-26
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
7
Registration Number
NCT03351231
Locations
🇺🇸

Local Institution, Baltimore, Maryland, United States

🇺🇸

University Of Alabama At Birmingham, Birmingham, Alabama, United States

🇺🇸

USC Norris Comprehensive Cancer Center, Los Angeles, California, United States

and more 1 locations

Nivolumab or Nivolumab Plus Cisplatin, in Combination With Radiotherapy in Patients With Cisplatin-ineligible or Eligible Locally Advanced Squamous Cell Head and Neck Cancer

Phase 3
Completed
Conditions
Squamous Cell Carcinoma of the Head and Neck
Interventions
Drug: Cetuximab
Biological: Nivolumab
Drug: Cisplatin
Radiation: Radiotherapy
First Posted Date
2017-11-21
Last Posted Date
2021-08-09
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
74
Registration Number
NCT03349710
Locations
🇺🇸

Cancer Treatment Centers of Phoneix, Goodyear, Arizona, United States

🇺🇸

Pinnacle Research Group, Llc, Anniston, Alabama, United States

🇺🇸

UCLA Health, Los Angeles, California, United States

and more 19 locations

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

Phase 1
Completed
Conditions
Malignancies Multiple
Interventions
First Posted Date
2017-11-17
Last Posted Date
2018-02-28
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
53
Registration Number
NCT03346837
Locations
🇺🇸

PPD, Austin, Texas, United States

An Investigational Study to Assess the Effect of BMS-986177 on Aspirin in Healthy Participants

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Aspirin
Drug: BMS-986177
Drug: Placebo
First Posted Date
2017-11-14
Last Posted Date
2018-01-19
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
20
Registration Number
NCT03341390
Locations
🇺🇸

PPD Austin Clinic, Austin, Texas, United States

An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer

Phase 2
Active, not recruiting
Conditions
Prostate Cancer
Interventions
First Posted Date
2017-11-09
Last Posted Date
2025-01-08
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
292
Registration Number
NCT03338790
Locations
🇺🇸

Local Institution - 0037, Miami, Florida, United States

🇺🇸

Local Institution - 0009, Marietta, Georgia, United States

🇺🇸

Local Institution - 0012, Detroit, Michigan, United States

and more 63 locations

A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

Phase 2
Completed
Conditions
Advanced Pancreatic Cancer
Interventions
First Posted Date
2017-11-08
Last Posted Date
2024-07-23
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
205
Registration Number
NCT03336216
Locations
🇺🇸

Local Institution - 0006, Philadelphia, Pennsylvania, United States

🇺🇸

Local Institution - 0007, Los Angeles, California, United States

🇺🇸

Dana Farber Cancer Institute., Boston, Massachusetts, United States

and more 38 locations

A Study of Experimental Medication BMS-986235 in Healthy Subjects

Phase 1
Completed
Conditions
Mediators of Inflammation
Interventions
Drug: BMS-986235
Other: Placebo
First Posted Date
2017-11-07
Last Posted Date
2022-03-31
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
122
Registration Number
NCT03335553
Locations
🇺🇸

PRA Health Sciences, Salt Lake City, Utah, United States

🇺🇸

Anaheim Clinical Trials, Anaheim, California, United States

An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment

Phase 1
Completed
Conditions
Advanced Cancer
Interventions
Biological: Nivolumab
Biological: Ipilimumab
Drug: IDO1 Inhibitor
Biological: Relatlimab
Biological: Cabiralizumab
Radiation: Radiation Therapy
First Posted Date
2017-11-07
Last Posted Date
2022-09-26
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
20
Registration Number
NCT03335540
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

🇺🇸

Local Institution - 0001, Chicago, Illinois, United States

🇺🇸

Local Institution - 0003, Pittsburgh, Pennsylvania, United States

and more 1 locations
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