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BRISTOL MYERS SQUIBB

🇺🇸United States
Ownership
-
Established
1989-01-01
Employees
30K
Market Cap
$97.5B
Website
https://www.bms.com/

Clinical Trials

1.7k

Active:133
Completed:1210

Trial Phases

6 Phases

Early Phase 1:1
Phase 1:574
Phase 2:352
+3 more phases

Drug Approvals

11

SFDA:10
CIMA_AEMPS:1

Drug Approvals

REVIA COMPRIMIDOS RECUBIERTOS

Approval Date
Jul 14, 2025
CIMA_AEMPS

Clinical Trials

Distribution across different clinical trial phases (1344 trials with phase data)• Click on a phase to view related trials

Phase 1
574 (42.7%)
Phase 2
352 (26.2%)
Phase 3
320 (23.8%)
Phase 4
53 (3.9%)
Not Applicable
41 (3.1%)
phase_1_2
2 (0.1%)
Early Phase 1
1 (0.1%)
phase_2_3
1 (0.1%)

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

Not Applicable
Not yet recruiting
Conditions
Advanced Solid Malignancies
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions
First Posted Date
2025-10-31
Last Posted Date
2025-10-31
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
252
Registration Number
NCT07223047
Locations
🇺🇸

Local Institution - 0001, San Antonio, Texas, United States

🇺🇸

Local Institution - 0007, Salt Lake City, Utah, United States

🇺🇸

Local Institution - 0011, Fairfax, Virginia, United States

and more 2 locations

A Study to Evaluate the Effect of KarXT on Urological Safety

Not Applicable
Not yet recruiting
Conditions
Schizophrenia
Interventions
Drug: Xanomeline/trospium chloride
First Posted Date
2025-10-28
Last Posted Date
2025-10-28
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
60
Registration Number
NCT07221877
Locations
🇺🇸

Local Institution - 0017, Little Rock, Arkansas, United States

🇺🇸

Local Institution - 0007, Bellflower, California, United States

🇺🇸

Local Institution - 0009, Culver City, California, United States

and more 13 locations

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Not Applicable
Not yet recruiting
Conditions
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Interventions
Drug: Pumitamig
Drug: Folfox
Drug: Capox
First Posted Date
2025-10-27
Last Posted Date
2025-10-27
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
690
Registration Number
NCT07221149
Locations
🇺🇸

Local Institution - 0284, Phoenix, Arizona, United States

🇺🇸

Local Institution - 0240, Los Angeles, California, United States

🇺🇸

Local Institution - 0277, Orange, California, United States

and more 133 locations

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Not Applicable
Not yet recruiting
Conditions
Untreated, Unresectable, or Metastatic Colorectal Cancer
Interventions
Drug: Pumitamig
Drug: FOLFOX
Drug: FOLFIRI
Drug: CAPOX
First Posted Date
2025-10-27
Last Posted Date
2025-10-27
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
990
Registration Number
NCT07221357
Locations
🇺🇸

Local Institution - 0263, Los Angeles, California, United States

🇺🇸

Local Institution - 0345, Orange, California, United States

🇺🇸

Local Institution - 0317, Sacramento, California, United States

and more 180 locations

A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East

Not yet recruiting
Conditions
β-thalassemia
Interventions
First Posted Date
2025-10-14
Last Posted Date
2025-10-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
200
Registration Number
NCT07215975
Locations
🇸🇦

Prince Muhammad bin Nasser Hospital, Jizan, Saudi Arabia

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News

FDA Proposes Streamlined Approval Pathway to Accelerate Biosimilar Drug Development

The U.S. FDA released draft guidance proposing to reduce human clinical study requirements for certain biosimilar drugs and treat them more like generic medications to accelerate market availability.

CAR-T Therapies from Cabaletta Bio and Bristol Myers Squibb Achieve Complete Remissions in Severe Inflammatory Muscle Disease

Experimental CAR-T therapies from Cabaletta Bio and Bristol Myers Squibb have induced complete remissions in patients with severe inflammatory muscle disease, according to dual clinical trial results presented this week.

Evotec Receives $25M Milestone Payment from Bristol Myers Squibb for Neuroscience Partnership Progress

Evotec received a $25 million payment from Bristol Myers Squibb for achieving scientific progress in their strategic neuroscience partnership focused on neurodegenerative diseases.

Bristol Myers Squibb Reports Promising CAR-T Cell Therapy Results for Three Autoimmune Diseases

Bristol Myers Squibb presented Phase 1 data from 71 patients showing its CD19 NEX-T CAR-T therapy achieved immune reset across three severe autoimmune diseases with 94% of patients remaining off immunosuppressive therapy.

Biokin Receives Record $250 Million ADC Milestone Payment from Bristol Myers Squibb

Biokin secured a $250 million milestone payment from Bristol Myers Squibb in October 2025, marking the largest antibody-drug conjugate milestone payment among Chinese innovative drug out-licensing deals.

Flagship Pioneering Launches Expedition Medicines with $50M Investment in AI-Driven Covalent Drug Discovery

Flagship Pioneering has launched Expedition Medicines with a $50 million investment, focusing on AI-driven drug discovery for cancer and immune diseases using covalent chemistry principles.

Takeda Expands AI Drug Discovery Partnership with Nabla Bio in $1B+ Deal

Takeda Pharmaceutical has signed a second multi-year AI partnership with Nabla Bio, potentially worth over $1 billion including milestone payments, to accelerate early-stage drug discovery using artificial intelligence.

iMDx Appoints Marketing VP to Spearhead Commercial Launch of Transplant Rejection Diagnostic

Insight Molecular Diagnostics (iMDx) has appointed Steven Tahmooressi as Vice President of Marketing to lead the commercial launch of its GraftAssureDx transplant rejection diagnostic kit.

Bristol Myers Squibb and Lilly Showcase Major Oncology Data at ESMO 2025

Bristol Myers Squibb will present data from over 50 studies at ESMO 2025, including first-in-class results from izalontamab brengitecan (iza-bren), an EGFRxHER3 bispecific ADC that received FDA Breakthrough Therapy designation for EGFR-mutated NSCLC.

Eli Lilly and AstraZeneca Emerge as Leading Candidates for Next Trump Administration Drug Pricing Deal

Wall Street analysts predict Eli Lilly and AstraZeneca are the most likely pharmaceutical companies to strike the next drug pricing deal with the Trump administration following Pfizer's September 29 agreement.

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