YALE UNIVERSITY

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1701-10-09

Employees: 10K

Market Cap: -

Website: http://www.yale.edu

Clinical Trials

A Study of APX005M in Combination With Nivolumab and Ipilimumab in Treatment Naïve Patients With Advanced Melanoma or Renal Cell Carcinoma (RCC)

Phase 1

Active, not recruiting

Conditions: Advanced Melanoma
Renal Cell Carcinoma

Interventions: Drug: Nivolumab
Drug: Ipilimumab
Drug: APX005M

First Posted Date: 2020-07-31

Last Posted Date: 2025-02-05

Lead Sponsor: Yale University

Target Recruit Count: 26

Registration Number: NCT04495257

Locations: 🇺🇸
Yale New Haven Hospital, New Haven, Connecticut, United States
🇺🇸
Yale Cancer Center, New Haven, Connecticut, United States

A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV

Phase 4

Active, not recruiting

Conditions: Tobacco Use Cessation

Interventions: Drug: Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler
Drug: Varenicline or bupropion
Behavioral: Contingency Management

First Posted Date: 2020-07-28

Last Posted Date: 2025-01-09

Lead Sponsor: Yale University

Target Recruit Count: 320

Registration Number: NCT04490057

Locations: 🇺🇸
SUNY Downstate STAR Clinic, Brooklyn, New York, United States
🇺🇸
Yale University School of Medicine, New Haven, Connecticut, United States
🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States

and more 1 locations

Smoking by IV Pulsed Nicotine

Early Phase 1

Completed

Conditions: Smoking Cessation

Interventions: Drug: Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s

First Posted Date: 2020-07-28

Last Posted Date: 2021-07-20

Lead Sponsor: Yale University

Target Recruit Count: 13

Registration Number: NCT04488744

Locations: 🇺🇸
Veterans Affairs Hospital, West Haven, Connecticut, United States

Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial

Phase 3

Completed

Conditions: SARS-CoV-2

Interventions: Drug: Standard of Care (SOC) and Colchicine+Rosuvastatin

First Posted Date: 2020-07-15

Last Posted Date: 2023-04-27

Lead Sponsor: Yale University

Target Recruit Count: 250

Registration Number: NCT04472611

Locations: 🇺🇸
Bridgeport Hospital, Bridgeport, Connecticut, United States
🇺🇸
Lawrence & Memorial Hospital, New London, Connecticut, United States
🇺🇸
Yale New Haven Hosptial System, New Haven, Connecticut, United States

and more 1 locations

Heart Watch Study: a Pragmatic Randomized Controlled Trial

Not Applicable

Completed

Conditions: Cardioversion
Atrial Fibrillation

Interventions: Device: Apple Watch
Device: Withings Move

First Posted Date: 2020-07-13

Last Posted Date: 2025-04-18

Lead Sponsor: Yale University

Target Recruit Count: 105

Registration Number: NCT04468321

Locations: 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
🇺🇸
Yale-New Haven Hospital, New Haven, Connecticut, United States

A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

Phase 1

Completed

Conditions: Early Course Schizophrenia Spectrum Disorder

Interventions: Drug: CVL-562 (PF-06412562) 1 mg
Drug: CVL-562 (PF-06412562) 4 mg
Drug: CVL-562 (PF-06412562) 15 mg
Drug: CVL-562 (PF-06412562) 25 mg
Other: Placebo

First Posted Date: 2020-07-07

Last Posted Date: 2025-03-10

Lead Sponsor: Yale University

Target Recruit Count: 112

Registration Number: NCT04457310

Locations: 🇺🇸
Stony Brook University, Stony Brook, New York, United States
🇺🇸
Columbia University, New York, New York, United States
🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States

and more 1 locations

Infrared Wraps Effect on Oxygenation of Diabetics Arm, Feet and Lower Leg

Not Applicable

Completed

Conditions: Diabetes

Interventions: Device: Active IR sock
Other: Placebo socks

First Posted Date: 2020-07-07

Last Posted Date: 2022-07-14

Lead Sponsor: Yale University

Target Recruit Count: 39

Registration Number: NCT04460612

Locations: 🇺🇸
Endocrine Associates Of Connecticut, Hamden, Connecticut, United States

COVID-19 Vaccine Messaging, Part 1

Not Applicable

Completed

Conditions: COVID-19
Vaccination

Interventions: Other: Control message
Other: Baseline message
Other: Personal freedom message
Other: Community interest message
Other: Anger message
Other: Self-interest message
Other: Economic benefit message
Other: Guilt message
Other: Embarrassment message
Other: Economic freedom message
Other: Trust in science message
Other: Not bravery message

First Posted Date: 2020-07-07

Last Posted Date: 2022-05-05

Lead Sponsor: Yale University

Target Recruit Count: 4000

Registration Number: NCT04460703

Locations: 🇺🇸
Yale University, New Haven, Connecticut, United States

Lidocaine Patches After Cesarean Section

Phase 3

Completed

Conditions: Postoperative Pain
Obstetric Pain
Opioid Use

Interventions: Drug: Lidocaine patch
Other: Placebo patch

First Posted Date: 2020-06-23

Last Posted Date: 2024-11-06

Lead Sponsor: Yale University

Target Recruit Count: 93

Registration Number: NCT04443569

Locations: 🇺🇸
Yale New Haven Hospital, New Haven, Connecticut, United States

Ertugliflozin in Chronic Heart Failure

Phase 2

Recruiting

Conditions: Heart Failure

Interventions: Drug: Ertugliflozin
Drug: Placebo
Drug: Metolazone

First Posted Date: 2020-06-18

Last Posted Date: 2025-03-07

Lead Sponsor: Yale University

Target Recruit Count: 60

Registration Number: NCT04438213

Locations: 🇺🇸
Yale School of Medicine, New Haven, Connecticut, United States

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