MEDICAL COLLEGE OF WISCONSIN

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1893-01-01

Employees: 5K

Market Cap: -

Website: http://www.mcw.edu

Clinical Trials

Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma

Phase 1

Not yet recruiting

Conditions: Multiple Myeloma

Interventions: Biological: BCMA-TGFβ CAR-T cells (1 x 10^6 cells/kg)
Biological: BCMA-TGFβ CAR-T cells (0.50 x 10^6 cells/kg)
Biological: BCMA-TGFβ CAR-T cells (0.75 x10^6 cells/kg)
Biological: BCMA-TGFβ CAR-T cells (2.5 x 10^6 cells/kg)
Biological: Maximum tolerated dose

First Posted Date: 2023-08-04

Last Posted Date: 2024-01-16

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 30

Registration Number: NCT05976555

Diabetes Education/Skills Training and Social Needs Resolution Intervention

Not Applicable

Recruiting

Conditions: Type 2 Diabetes

Interventions: Behavioral: DM Social Needs
Behavioral: Usual Care

First Posted Date: 2023-07-07

Last Posted Date: 2023-10-19

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 100

Registration Number: NCT05935410

Locations: 🇺🇸
Aprill Dawson, Milwaukee, Wisconsin, United States

Passive Limb Movement Study

Not Applicable

Recruiting

Conditions: Stroke
Ischemic
Vascular Diseases

Interventions: Device: Ischemic Conditioning

First Posted Date: 2023-07-07

Last Posted Date: 2023-07-07

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 30

Registration Number: NCT05935670

Locations: 🇺🇸
Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Determining Individualized Cancer Therapy in Pancreatic Cancer

Recruiting

Conditions: Pancreatic Neoplasms

First Posted Date: 2023-06-22

Last Posted Date: 2024-02-08

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 1000

Registration Number: NCT05914987

Locations: 🇺🇸
Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage

Phase 1

Recruiting

Conditions: Acute Kidney Injury
HIE

Interventions: Drug: Single Dose Theophylline
Drug: Repeat Dose Theophylline

First Posted Date: 2023-05-11

Last Posted Date: 2024-12-04

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 54

Registration Number: NCT05853601

Locations: 🇺🇸
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals

Phase 2

Recruiting

Conditions: Fragility
Aging
Endothelial Dysfunction

Interventions: Other: Ischemic Conditioning

First Posted Date: 2023-04-11

Last Posted Date: 2023-07-28

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 60

Registration Number: NCT05808686

Locations: 🇺🇸
Froedtert Hospital, Wauwatosa, Wisconsin, United States

MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

Not Applicable

Recruiting

Conditions: Acute Myeloid Leukemia in Remission
Acute Lymphoblastic Leukemia in Remission
Myelodysplasia
Chronic Myelogenous Leukemia - Chronic Phase
Chronic Myelogenous Leukemia With Crisis of Blast Cells
Biphenotypic Acute Leukemia
Burkitt Leukemia
Leukemia
Other Malignant Hematologic Diseases in Remission
Chronic Myelogenous Leukemia, Accelerated Phase

Interventions: Device: Magnetic-Activated Cell Sorter (CliniMACS, Miltenyi)

First Posted Date: 2023-04-03

Last Posted Date: 2023-06-13

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 40

Registration Number: NCT05794880

Locations: 🇺🇸
Children's Wisconsin, Milwaukee, Wisconsin, United States

Pilot Study Lp299v Supplementation in Chronic Heart Failure

Not Applicable

Recruiting

Conditions: Heart Failure
Heart Failure with Reduced Ejection Fraction
Heart Failure, Systolic
Heart Failure with Preserved Ejection Fraction
Heart Failure, Diastolic

Interventions: Other: Freeze Dried Potato Starch Capsule
Other: Lactobacillus Plantarum 299v Freeze Dried Capsule

First Posted Date: 2023-03-03

Last Posted Date: 2024-11-26

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 20

Registration Number: NCT05752760

Locations: 🇺🇸
Medical College of Wisconsin, Milwaukee, Wisconsin, United States

Lidocaine Patches in Elderly Patients With Traumatic Rib Fractures

Phase 4

Recruiting

Conditions: Rib Fractures

Interventions: Other: Placebo Patch
Drug: 4% Lidocaine Patch

First Posted Date: 2023-02-06

Last Posted Date: 2023-10-24

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 93

Registration Number: NCT05714631

Locations: 🇺🇸
Abdul Hafiz Al Tannir, Milwaukee, Wisconsin, United States

Striated Esophageal Motor Function Modulation in Health and Disease

Not Applicable

Recruiting

Conditions: Dysphagia, Esophageal

Interventions: Device: Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction
Device: Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device

First Posted Date: 2023-02-01

Last Posted Date: 2024-03-20

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 557

Registration Number: NCT05708885

Locations: 🇺🇸
Medical College of Wisconsin, Milwaukee, Wisconsin, United States

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