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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
Country
🇺🇸
United States
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Clinical Trials
Related News
A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide
Phase 2
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: Placebo
Drug: Esketamine
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First Posted Date
2014-05-07
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
68
Registration Number
NCT02133001
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A Pharmacokinetic, Safety and Tolerability Study of Esketamine in Healthy Elderly and Adult Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Esketamine
Drug: Placebo
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First Posted Date
2014-05-02
Last Posted Date
2014-07-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
34
Registration Number
NCT02129088
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A Bioequivalence Study of Norgestimate /Ethinyl Estradiol (NGM/EE) Tablets Manufactured at 2 Different Facilities
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Norgestimate /Ethinyl estradiol tablets (NGM/EE) (Wet Process)
Drug: Norgestimate /Ethinyl estradiol tablets (NGM/EE) (Dry Process)
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First Posted Date
2014-04-30
Last Posted Date
2014-10-03
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
101
Registration Number
NCT02127593
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A Crossover Study to Evaluate Relative Bioavailability of Two JNJ-54781532 Tablet Formulations in Healthy Adult Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Formulation 2
Drug: Formulation 1
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First Posted Date
2014-04-21
Last Posted Date
2014-06-26
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
20
Registration Number
NCT02117505
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Cognitive Health in Ageing Register: Investigational, Observational and Trial Studies in Dementia Research: Prospective Readiness Cohort Study
Completed
Conditions
Plaque, Amyloid
Alzheimer's Disease
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First Posted Date
2014-04-15
Last Posted Date
2025-04-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
1136
Registration Number
NCT02114372
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A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
Phase 3
Completed
Conditions
Rheumatic Diseases
Heart Failure
Respiratory Insufficiency
Stroke Acute
Infectious Diseases
Interventions
Drug: Rivaroxaban, 10 mg
Drug: Placebo
Drug: Rivaroxaban, 7.5 mg
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First Posted Date
2014-04-11
Last Posted Date
2019-11-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
12024
Registration Number
NCT02111564
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A Study to Evaluate the Effect of Intranasal Esketamine on Cognitive Functioning in Healthy Subjects
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Esketamine
Drug: Placebo
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First Posted Date
2014-03-21
Last Posted Date
2014-10-16
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
24
Registration Number
NCT02094378
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Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants
Phase 1
Completed
Conditions
Psychotic Disorders
Schizophrenia
Bipolar Disorder
Depressive Disorder
Interventions
Drug: Aripiprazole, oral formulation
Drug: Olanzapine, oral formulation
Drug: Paliperidone, oral formulation
Drug: Quetiapine, oral formulation
Drug: Risperidone, oral formulation
Drug: Paliperidone, LAI
Drug: Risperidone, LAI
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First Posted Date
2014-03-14
Last Posted Date
2015-10-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
305
Registration Number
NCT02087579
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A Study of DOXIL/CAELYX in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer
Phase 1
Completed
Conditions
Neoplasms
Interventions
Drug: DOXIL/CAELYX reference product (Treatment A)
Drug: DOXIL/CAELYX test product (Treatment B)
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First Posted Date
2014-03-07
Last Posted Date
2016-11-11
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
35
Registration Number
NCT02081495
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Bioavailability and Pharmacokinetics Study of Sirukumab in Healthy Male Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Sirukumab (IV infusion)
Drug: Sirukumab (SC injection with PFS-U)
Drug: Sirukumab (SC injection with PFS-AI)
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First Posted Date
2014-03-05
Last Posted Date
2016-03-09
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
144
Registration Number
NCT02079545
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