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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
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🇺🇸
United States
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Clinical Trials
Related News
Study of Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC), Chemo-Naive, Who Received a Prior Diethylstilbestrol Therapy
Phase 2
Completed
Conditions
Prostatic Neoplasms
Interventions
Drug: Abiraterone acetate
Drug: Prednisone
Drug: Androgen deprivation therapy (ADT)
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First Posted Date
2014-08-15
Last Posted Date
2020-01-13
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
46
Registration Number
NCT02217566
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Pharmacokinetic Study of JNJ-42756493 in Healthy Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42756493 10 mg tablet
Drug: JNJ-42756493 10 mg Oral Solution
Drug: JNJ-61818549
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First Posted Date
2014-08-15
Last Posted Date
2015-01-08
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
8
Registration Number
NCT02218073
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A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-54861911
Drug: Caffeine
Drug: Midazolam
Drug: Tolbutamide
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First Posted Date
2014-08-07
Last Posted Date
2015-11-24
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
16
Registration Number
NCT02211079
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A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis With Randomized Withdrawal and Retreatment
Phase 3
Completed
Conditions
Psoriasis
Interventions
Drug: Guselkumab 100 mg
Drug: Placebo for guselkumab
Drug: Placebo for adalimumab
Drug: Adalimumab
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First Posted Date
2014-08-04
Last Posted Date
2021-07-22
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
992
Registration Number
NCT02207244
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A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis
Phase 3
Completed
Conditions
Psoriasis
Interventions
Drug: Guselkumab 100 mg
Drug: Placebo for guselkumab
Drug: Placebo for adalimumab
Drug: Adalimumab
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First Posted Date
2014-08-04
Last Posted Date
2021-07-23
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
837
Registration Number
NCT02207231
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A Study of Guselkumab in Participants With Moderate to Severe Plaque-type Psoriasis and an Inadequate Response to Ustekinumab
Phase 3
Completed
Conditions
Psoriasis
Interventions
Drug: Ustekinumab
Drug: Guselkumab
Drug: Placebo for guselkumab
Drug: Placebo for ustekinumab
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First Posted Date
2014-07-29
Last Posted Date
2017-09-12
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
872
Registration Number
NCT02203032
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A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy
Phase 3
Completed
Conditions
Epilepsy
Interventions
Drug: Levetiracetam
Drug: Topiramate
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First Posted Date
2014-07-28
Last Posted Date
2025-04-29
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
63
Registration Number
NCT02201251
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A Study to Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-54861911, 25 mg
Drug: Itraconazole 200 mg
Drug: Clarithromycin 500 mg
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First Posted Date
2014-07-23
Last Posted Date
2014-10-15
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
13
Registration Number
NCT02197884
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A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma
Phase 3
Completed
Conditions
Multiple Myeloma
Interventions
Drug: Velcade
Drug: Melphalan
Drug: Prednisone
Drug: Daratumumab IV
Drug: Dexamethasone
Drug: Daratumumab SC
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First Posted Date
2014-07-21
Last Posted Date
2025-05-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
706
Registration Number
NCT02195479
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A Study of Golimumab in Participants With Active Ankylosing Spondylitis
Phase 3
Completed
Conditions
Ankylosing Spondylitis
Interventions
Drug: Placebo
Drug: Golimumab
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First Posted Date
2014-07-10
Last Posted Date
2017-12-22
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
208
Registration Number
NCT02186873
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