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JANSSEN RESEARCH & DEVELOPMENT, LLC
🇺🇸
United States
Country
🇺🇸
United States
Ownership
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Clinical Trials
Related News
A Study to Evaluate the Pharmacokinetics of JNJ-38518168 in Patients With Mild and Moderate Hepatic Impairment Compared With Patients With Normal Hepatic Function
Phase 1
Completed
Conditions
Hepatic Impairment
Interventions
Drug: JNJ-38518168
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First Posted Date
2013-05-29
Last Posted Date
2016-05-12
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
28
Registration Number
NCT01863784
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A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Phase 2
Terminated
Conditions
Rheumatoid Arthritis
Interventions
Drug: JNJ-38518168
Drug: Placebo
Drug: Methotrexate
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First Posted Date
2013-05-24
Last Posted Date
2015-07-09
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
21
Registration Number
NCT01862224
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Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003
Phase 3
Completed
Conditions
Arthritis, Rheumatoid
Interventions
Drug: Sirukumab 100 mg
Drug: Sirukumab 50 mg
Drug: Placebo
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First Posted Date
2013-05-17
Last Posted Date
2019-05-06
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
1820
Registration Number
NCT01856309
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A Study of the Bruton's Tyrosine Kinase Inhibitor, PCI-32765 (Ibrutinib), in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Non-Germinal Center B-Cell Subtype of Diffuse Large B-Cell Lymphoma
Phase 3
Completed
Conditions
Lymphoma
Interventions
Drug: Placebo
Drug: Ibrutinib
Drug: Rituximab
Drug: Cyclophosphamide
Drug: Doxorubicin
Drug: Vincristine
Drug: Prednisone (or equivalent)
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First Posted Date
2013-05-16
Last Posted Date
2025-02-04
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
838
Registration Number
NCT01855750
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A Study of Decitabine (DACOGEN) in Sequential Administration With Cytarabine in Children With Relapsed or Refractory Acute Myeloid Leukemia
Phase 1
Terminated
Conditions
Acute Myeloid Leukemia
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First Posted Date
2013-05-14
Last Posted Date
2019-06-17
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
17
Registration Number
NCT01853228
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A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Phase 3
Completed
Conditions
Fallopian Tube Neoplasms
Ovarian Neoplasms
Peritoneal Neoplasms
Interventions
Drug: Trabectedin
Drug: DOXIL
Drug: Dexamethasone
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First Posted Date
2013-05-03
Last Posted Date
2019-04-01
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
581
Registration Number
NCT01846611
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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42721458 in Healthy Male Participants
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42721458 (single dose)
Drug: Placebo (single dose)
Drug: JNJ-42721458 (multiple doses)
Drug: Placebo (multiple doses)
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First Posted Date
2013-04-25
Last Posted Date
2014-05-06
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
108
Registration Number
NCT01840501
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A Study of Abiraterone Acetate Plus Prednisone in Asymptomatic or Mildly Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer
Conditions
Prostate Neoplasms
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First Posted Date
2013-04-17
Last Posted Date
2018-11-07
Lead Sponsor
Janssen Research & Development, LLC
Registration Number
NCT01834209
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A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-54861911 in Healthy Volunteers Compared With Placebo
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-54861911 9 mg
Drug: JNJ-54861911 81 mg
Drug: JNJ-54861911 tbd
Drug: JNJ-54861911 27 mg
Drug: Placebo
Drug: JNJ-54861911 1mg
Drug: JNJ-54861911 3 mg
Drug: JNJ-54861911 160 mg
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First Posted Date
2013-04-10
Last Posted Date
2014-11-10
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
56
Registration Number
NCT01827982
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The Effects of JNJ-42165279 on the Neural Basis of Anxiety Disorders in Healthy Male Volunteers
Phase 1
Completed
Conditions
Healthy
Interventions
Drug: JNJ-42165279 (100 mg)
Drug: Placebo
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First Posted Date
2013-04-09
Last Posted Date
2014-10-15
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
43
Registration Number
NCT01826786
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