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Lyell Immunopharma Inc

Lyell Immunopharma Inc logo
🇺🇸United States
Ownership
Public
Established
2018-01-01
Employees
251
Market Cap
$373.7M
Website
http://www.lyell.com

Clinical Trials

5

Active:0
Completed:0

Trial Phases

1 Phases

Phase 1:4

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (4 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (100.0%)

A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE)

Phase 1
Withdrawn
Conditions
Lupus Nephritis
Systemic Lupus Erythematosus
Interventions
First Posted Date
2023-12-01
Last Posted Date
2025-02-10
Lead Sponsor
Lyell Immunopharma, Inc.
Target Recruit Count
30
Registration Number
NCT06153095
Locations
🇺🇸

University of California, Los Angeles (UCLA) Medical Center, Los Angeles, California, United States

🇺🇸

University of California San Francisco, San Francisco, California, United States

🇺🇸

University of Iowa, Iowa City, Iowa, United States

and more 1 locations

A Biomarker Screening Protocol for Participants With Solid Tumors

Terminated
Conditions
Triple Negative Breast Cancer
Non-small Cell Lung Cancer
Non Small Cell Lung Cancer
Non Small Cell Lung Cancer Metastatic
Non-Small Cell Carcinoma of Lung, TNM Stage 4
Advanced Breast Cancer
Advanced Lung Carcinoma
NSCLC
NSCLC, Recurrent
NSCLC Stage IV
First Posted Date
2023-06-06
Last Posted Date
2025-07-01
Lead Sponsor
Lyell Immunopharma, Inc.
Target Recruit Count
10
Registration Number
NCT05891197
Locations
🇺🇸

Accellacare, Rocky Mount, North Carolina, United States

Study of LYL314 in Aggressive Large B-Cell Lymphoma

Phase 1
Recruiting
Conditions
Relapsed Non-Hodgkin Lymphoma
Refractory Non-Hodgkin Lymphoma
Non-Hodgkin Lymphoma
Large B-cell Lymphoma
Interventions
First Posted Date
2023-04-24
Last Posted Date
2025-06-15
Lead Sponsor
Lyell Immunopharma, Inc.
Target Recruit Count
270
Registration Number
NCT05826535
Locations
🇺🇸

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

🇺🇸

University of California-Irvine Medical Center, Irvine, California, United States

🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

and more 14 locations

A Study to Investigate LYL845 in Adults With Solid Tumors

Phase 1
Terminated
Conditions
Melanoma
Non-small Cell Lung Cancer
Colorectal Cancer
Interventions
First Posted Date
2022-10-10
Last Posted Date
2025-07-01
Lead Sponsor
Lyell Immunopharma, Inc.
Target Recruit Count
39
Registration Number
NCT05573035
Locations
🇺🇸

UC Davis Coomprehensive Cancer Center, Sacramento, California, United States

🇺🇸

UCLA Medical Center, Santa Monica, California, United States

🇺🇸

Stanford University, Stanford, California, United States

and more 15 locations

A Study to Investigate LYL797 in Adults With Solid Tumors

Phase 1
Terminated
Conditions
Triple Negative Breast Cancer
TNBC - Triple-Negative Breast Cancer
Non-small Cell Lung Cancer
Non Small Cell Lung Cancer
Non Small Cell Lung Cancer Metastatic
Non-Small Cell Carcinoma of Lung, TNM Stage 4
Advanced Breast Cancer
Advanced Lung Carcinoma
NSCLC
NSCLC, Recurrent
Interventions
First Posted Date
2022-03-10
Last Posted Date
2025-07-01
Lead Sponsor
Lyell Immunopharma, Inc.
Target Recruit Count
57
Registration Number
NCT05274451
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

🇺🇸

University of California, Los Angeles, Santa Monica, California, United States

🇺🇸

Yale New Haven Hospital, New Haven, Connecticut, United States

and more 13 locations

News

Lyell's IMPT-314 CAR T-cell Therapy Shows Promise in B-Cell Lymphoma Trial

Lyell's IMPT-314 demonstrated a 94% objective response rate and a 71% complete response rate in CAR T-naive patients with large B-cell lymphoma.

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