Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cisplatin and Oral Vinorelbine in Chemotherapy Naïve Patients Affected by Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer With High Thymidylate Synthase Expression
- Conditions
- Carcinoma, Non-Small-Cell LungSecondaryAdvanced Stage IIIBHigh Thymidylate Synthase Expression
- Interventions
- First Posted Date
- 2016-09-29
- Last Posted Date
- 2018-01-16
- Target Recruit Count
- 2
- Registration Number
- NCT02919462
- Locations
- 🇮🇹
U.O. Oncologia Medica, Faenza, RA, Italy
🇮🇹U.O. Oncologia Ospedale degli Infermi, Rimini, Italy
🇮🇹Ircc Irst, Meldola, FC, Italy
Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate After Curative Resection for Stage IV Colorectal Cancer.
- Conditions
- Stage IV Colorectal CancerCurative Resection
- Interventions
- Biological: autologous dendritic cells loaded with autologous tumour homogenate
- First Posted Date
- 2016-09-29
- Last Posted Date
- 2020-04-21
- Target Recruit Count
- 19
- Registration Number
- NCT02919644
- Locations
- 🇮🇹
UO Immunoterapia e Laboratorio TCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) S.r.l IRCCS, Meldola, FC, Italy
🇮🇹CRO-IRCCS Aviano, Aviano, Italy
Italian Study Of Validation Of Angiogenesis Polymorphisms In HCC Patients Treated With Sorafenib
- Conditions
- Hepatocellular Carcinoma
- Interventions
- Procedure: blood sample collection
- First Posted Date
- 2016-06-01
- Last Posted Date
- 2021-02-26
- Target Recruit Count
- 160
- Registration Number
- NCT02786342
- Locations
- 🇮🇹
Azienda Ospedaliera Universitaria Pisana, Pisa, PI, Italy
🇮🇹AOU di Cagliari - PO San Giovanni di Dio, Cagliari, CA, Italy
🇮🇹Oncologia medica , PO FAENZA, Ausl della Romagna, Faenza, RA, Italy
Peptide Receptor Radionuclide Therapy With 177Lu-Dotatate Associated With Metronomic Capecitabine In Patients Affected By Aggressive Gastro-Etero-Pancreatic Neuroendocrine Tumors
- Conditions
- Neuroendocrine TumorsGastro Entero Pancreatic Neuroendocrine Tumors
- Interventions
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2025-01-13
- Target Recruit Count
- 39
- Registration Number
- NCT02736500
- Locations
- 🇮🇹
Lisa Bodei, Milan, Italy
🇮🇹Giovanni Paganelli, Meldola, FC, Italy
177Lutethium - Peptide Receptor Radionuclide Therapy (Lu-PRRT) Plus Capecitabine Versus Lu-PRRT in FDG Positive, Gastro-entero-pancreatic Neuroendocrine Tumors
- Conditions
- Gastro-entero-pancreatic Neuroendocrine Tumors
- Interventions
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2025-01-13
- Target Recruit Count
- 35
- Registration Number
- NCT02736448
- Locations
- 🇮🇹
Irst Irccs, Meldola, FC, Italy
Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients.
- Conditions
- Malignant MelanomaAdjuvant Drug TherapyVaccin Therapy
- Interventions
- Biological: Autologous Dendritic Cell vaccine
- First Posted Date
- 2016-03-24
- Last Posted Date
- 2020-04-22
- Target Recruit Count
- 12
- Registration Number
- NCT02718391
- Locations
- 🇮🇹
UO Oncologia Medica, IRCCS IRST, Meldola (FC), FC, Italy
🇮🇹UO Immunoterapia e laboratorio TCS, IRST IRCCS, Meldola, FC, Italy
3 Tesla Magnetic Resonance Guided High Intensity Focused Ultrasound in the Treatment of Pain From Bone Metastases of Solid Tumors
- Conditions
- Solid Tumors
- Interventions
- Procedure: MR-HIFU TreatmentDrug: MR contrast media and medicationsProcedure: MR images
- First Posted Date
- 2016-03-24
- Last Posted Date
- 2022-06-30
- Target Recruit Count
- 12
- Registration Number
- NCT02718404
- Locations
- 🇮🇹
Centro di Osteoncologia e Tumori Rari (CDO-TR) IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) S.r.l, Meldola, FC, Italy
Implementing an Evidence-based Computerized Decision Support System Linked to Electronic Health Records to Improve Care for Cancer Patients
- Conditions
- Medical Oncology
- Interventions
- Other: Control groupOther: computer reminders on clinical practice
- First Posted Date
- 2016-01-01
- Last Posted Date
- 2017-02-09
- Target Recruit Count
- 15431
- Registration Number
- NCT02645357
- Locations
- 🇮🇹
Oncologia Medica, IRST IRCCS, Meldola, Meldola, Italy
Olaparib as Salvage Treatment for Cisplatin-resistant Germ Cell Tumor
- First Posted Date
- 2015-08-27
- Last Posted Date
- 2025-01-30
- Target Recruit Count
- 18
- Registration Number
- NCT02533765
- Locations
- 🇮🇹
Istituto Nazionale Tumori IRCCS "Fondazione G.Pascale", Napoli, Italy
🇮🇹U.O Oncologia Medica, IRST IRCCS, Meldola, FC, Italy
Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-DOTATATE in Advanced Gastro-entero Pancreatic Neuroendocrine Tumors
- Conditions
- Neuroendocrine Tumors
- Interventions
- First Posted Date
- 2015-07-03
- Last Posted Date
- 2025-01-13
- Target Recruit Count
- 70
- Registration Number
- NCT02489604
- Locations
- 🇮🇹
Irst Irccs, Meldola, FC, Italy