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MILLENNIUM PHARMACEUTICALS, INC.

MILLENNIUM PHARMACEUTICALS, INC. logo
🇺🇸United States
Ownership
Subsidiary
Established
1993-01-01
Employees
1K
Market Cap
-
Website
http://www.takedaoncology.com

IXAZOMIB Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma

Phase 3
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2013-05-09
Last Posted Date
2023-07-21
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
705
Registration Number
NCT01850524

Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib

Phase 1
Completed
Conditions
Lymphoma
Solid Tumors
Interventions
First Posted Date
2013-05-01
Last Posted Date
2019-03-25
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
55
Registration Number
NCT01844583

Pharmacokinetics Study of Oral Ixazomib (MLN9708) in Relapsed/Refractory Multiple Myeloma and Advanced Solid Tumors Participants With Normal Renal Function or Severe Renal Impairment

Phase 1
Completed
Conditions
Multiple Myeloma
Advanced Solid Tumors
Interventions
First Posted Date
2013-04-12
Last Posted Date
2019-06-10
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
41
Registration Number
NCT01830816
Locations
🇺🇸

Mary Crowley Cancer Research Centers Medical City, Dallas, Texas, United States

🇺🇸

Institute of Oncology Hematology Biomedical Research, Laredo, Texas, United States

🇺🇸

University of Kansas Cancer Center, Clinical Research Center, Fairway, Kansas, United States

and more 8 locations

Study of MLN4924 Plus Azacitidine in Treatment-naive Participants With Acute Myelogenous Leukemia (AML) Who Are 60 Years or Older

Phase 1
Completed
Conditions
Acute Myelogenous Leukemia
Interventions
First Posted Date
2013-03-20
Last Posted Date
2020-03-03
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
64
Registration Number
NCT01814826
Locations
🇺🇸

Hospital Corporation of America-HealthOne, LLC, Denver, Colorado, United States

🇺🇸

UNC-Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States

🇺🇸

University of Miami School of Medicine, Miami, Florida, United States

and more 5 locations

Mass Balance, Pharmacokinetics and Metabolism Study of Alisertib

Phase 1
Completed
Conditions
Advanced Solid Tumors
Lymphoma
Interventions
Drug: [^14C]-alisertib
First Posted Date
2012-10-26
Last Posted Date
2018-10-31
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
3
Registration Number
NCT01714947
Locations
🇺🇸

Comprehensive Clinical Development, Tacoma, Washington, United States

Study in Japan and Ex-Japan to Characterize the Pharmacokinetic and Pharmacodynamic Response to Orteronel (TAK-700) in Chemotherapy-Naive Participants With Castration-Resistant Prostate Cancer

Phase 1
Completed
Conditions
Prostate Cancer
Interventions
First Posted Date
2012-08-16
Last Posted Date
2018-03-20
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
137
Registration Number
NCT01666314
Locations
🇺🇸

Urology Cancer Center, PC, Omaha, Nebraska, United States

Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis

Phase 3
Terminated
Conditions
Relapsed or Refractory Systemic Light Chain Amyloidosis
Interventions
First Posted Date
2012-08-08
Last Posted Date
2024-04-25
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
177
Registration Number
NCT01659658
Locations
🇺🇸

Indiana University School of Medicine, Indianapolis, Indiana, United States

🇺🇸

University of Cincinnati, Cincinnati, Ohio, United States

🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

and more 63 locations

Phase 1 Pharmacokinetic Study of Oral Ixazomib Plus Lenalidomide and Dexamethasone in Adult Asian Participants With Relapsed and/or Refractory Multiple Myeloma

Phase 1
Completed
Conditions
Multiple Myeloma
Interventions
First Posted Date
2012-07-20
Last Posted Date
2018-11-08
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
43
Registration Number
NCT01645930

Study of TAK-733 in Combination With Alisertib in Adult Patients With Advanced Nonhematologic Malignancies

Phase 1
Withdrawn
Conditions
Advanced Nonhematologic Malignancies
Interventions
First Posted Date
2012-06-07
Last Posted Date
2013-11-01
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Registration Number
NCT01613261
Locations
🇺🇸

South Texas Accelerated Research Therapeutics (START), San Antonio, Texas, United States

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)

Phase 3
Completed
Conditions
Primary Cutaneous Anaplastic Large Cell Lymphoma
Mycosis Fungoides
Cutaneous T-Cell Lymphoma
Interventions
First Posted Date
2012-04-17
Last Posted Date
2021-01-05
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Target Recruit Count
131
Registration Number
NCT01578499
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