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UNIVERSITY OF CAPE TOWN

🇿🇦South Africa

Country: 🇿🇦South Africa

Ownership: Private

Established: 1829-10-01

Employees: 51

Market Cap: -

Website: http://www.rcips.uct.ac.za

Clinical Trials

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry

Completed

Conditions: Unstable Angina
Acute Coronary Syndrome
ST Elevated Myocardial Infarction
Non ST Elevation Myocardial Infarction

Interventions: Other: No Intervention - Observational Registry

First Posted Date: 2021-05-14

Last Posted Date: 2023-06-26

Lead Sponsor: University of Cape Town

Target Recruit Count: 870

Registration Number: NCT04887571

Locations: 🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa
🇿🇦
Victoria Hospital, Cape Town, Western Cape, South Africa
🇿🇦
New Somerset Hospital, Cape Town, Western Cape, South Africa

and more 1 locations

Remote Ischaemic Conditioning in STEMI Patients in AFRICA

Not Applicable

Recruiting

Conditions: STEMI
Myocardial Reperfusion Injury
Remote Ischaemic Conditioning

Interventions: Device: Sham-control
Device: Remote Ischaemic Conditioning (RIC)

First Posted Date: 2021-03-24

Last Posted Date: 2025-04-03

Lead Sponsor: University of Cape Town

Target Recruit Count: 1400

Registration Number: NCT04813159

Locations: 🇲🇿
Hospital Central de Mpauto, Maputo, Mozambique
🇸🇳
Hopital Principal de Dakar, Dakar, Senegal
🇰🇪
Coast General Teaching Hospital, Mombasa, Kenya

and more 17 locations

An Observational Study of Distress, Immune Function, and Pain in HIV.

Completed

Conditions: Immune System and Related Disorders
Central Sensitisation
Chronic Pain
Distress, Emotional
HIV

Interventions: Other: Pain

First Posted Date: 2021-02-17

Last Posted Date: 2023-11-29

Lead Sponsor: University of Cape Town

Target Recruit Count: 107

Registration Number: NCT04757987

Locations: 🇿🇦
Community Health Clinic [name withheld due to risk to participants], [City Withheld Due To Risk To Participants], Western Cape, South Africa

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis

Phase 2

Active, not recruiting

Conditions: HIV Status
Tuberculous Pericarditis

Interventions: Drug: high dose Rifampicin (RIF)

First Posted Date: 2020-08-21

Last Posted Date: 2025-04-13

Lead Sponsor: University of Cape Town

Target Recruit Count: 60

Registration Number: NCT04521803

Locations: 🇿🇦
Nelson Mandela Academic Hospital, Mthatha, Eastern Cape, South Africa
🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa

Catalysing the Containment of COVID-19

Phase 2

Terminated

Conditions: COVID-19

Interventions: Drug: Placebo
Drug: Nitazoxanide

First Posted Date: 2020-08-21

Last Posted Date: 2022-08-16

Lead Sponsor: University of Cape Town

Target Recruit Count: 322

Registration Number: NCT04523090

Locations: 🇿🇦
The Aurum Institute, Tembisa, Gauteng, South Africa
🇿🇦
University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa
🇿🇦
Perinatal HIV Research Unit, Klerksdorp, North West, South Africa

and more 1 locations

African Covid-19 Critical Care Outcomes Study

Conditions: Severe Acute Respiratory Syndrome Coronavirus 2

First Posted Date: 2020-04-29

Last Posted Date: 2020-09-10

Lead Sponsor: University of Cape Town

Target Recruit Count: 2000

Registration Number: NCT04367207

Locations: 🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa

Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19

Phase 3

Withdrawn

Conditions: Covid-19
HIV

Interventions: Drug: Chloroquine or hydroxychloroquine

First Posted Date: 2020-04-24

Last Posted Date: 2020-08-18

Lead Sponsor: University of Cape Town

Registration Number: NCT04360759

Locations: 🇿🇦
Khayelitsha Hospital, Cape Town, Western Cape, South Africa
🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa

Telemedicine for First Trimester Abortion in South Africa

Not Applicable

Conditions: Abortion in First Trimester

Interventions: Other: Telemedicine

First Posted Date: 2020-04-07

Last Posted Date: 2021-04-30

Lead Sponsor: University of Cape Town

Target Recruit Count: 900

Registration Number: NCT04336358

Locations: 🇿🇦
Karl Bremer Hospital, Bellville, Western Cape, South Africa
🇿🇦
Vanguard CHC, Cape Town, Western Cape, South Africa
🇿🇦
Michael Mapongwana CHC, Khayelitsha, Western Cape, South Africa

and more 1 locations

Xpert Active Case-finding Trial 3 (XACT-3)

Not Applicable

Active, not recruiting

Conditions: Tuberculosis

Interventions: Other: GeneXpert Ultra
Other: GeneXpert Edge

First Posted Date: 2020-03-10

Last Posted Date: 2024-07-16

Lead Sponsor: University of Cape Town

Target Recruit Count: 3394

Registration Number: NCT04303104

Locations: 🇲🇿
Bindiya Meggi, Maputo, Mozambique
🇿🇦
University of Cape Town, Cape Town, Western Cape, South Africa
🇿🇲
Helen Ayles, Lusaka, Zambia

and more 1 locations

Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion

Phase 2

Recruiting

Conditions: Tuberculosis, Pulmonary

Interventions: Drug: Placebo oral tablet
Drug: Atorvastatin 40mg

First Posted Date: 2019-11-01

Last Posted Date: 2024-08-23

Lead Sponsor: University of Cape Town

Target Recruit Count: 220

Registration Number: NCT04147286

Locations: 🇿🇦
General Medicine & Global Health, Cape Heart Institute, Faculty of Health Sciences, University of Cape Town, Observatory, WC, South Africa

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