UNIVERSITY OF CAPE TOWN

🇿🇦South Africa

Country: 🇿🇦South Africa

Ownership: Private

Established: 1829-10-01

Employees: 51

Market Cap: -

Website: http://www.rcips.uct.ac.za

Clinical Trials

Peer Support to Mitigate the Impact of Stigma in Young HIV+ Pregnant & Postpartum Women

Not Applicable

Completed

Conditions: Hiv

Interventions: Behavioral: Peer support intervention

First Posted Date: 2019-07-30

Last Posted Date: 2022-05-18

Lead Sponsor: University of Cape Town

Target Recruit Count: 120

Registration Number: NCT04036851

Locations: 🇿🇦
Gugulethu Community Health Centre, Cape Town, Western Cape, South Africa

The ASOS-2 Trial Maternal Mortality Sub-study

Conditions: Maternal Mortality
Africa
Cesarean Section

Interventions: Procedure: Cesarean section

First Posted Date: 2019-07-23

Last Posted Date: 2020-01-29

Lead Sponsor: University of Cape Town

Target Recruit Count: 100

Registration Number: NCT04029207

Locations: 🇿🇦
Groote Schuur Hospital, Observatory, Western Cape, South Africa

Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial

Phase 2

Completed

Conditions: HIV Infections

Interventions: Drug: Dolutegravir 50 mg
Drug: Placebo

First Posted Date: 2019-06-19

Last Posted Date: 2024-10-01

Lead Sponsor: University of Cape Town

Target Recruit Count: 192

Registration Number: NCT03991013

Locations: 🇿🇦
Khayelitsha Site B/Ubuntu Community Health Clinic, Cape Town, Western Cape, South Africa

Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBM

Phase 2

Completed

Conditions: Tuberculosis Meningitis
HIV-1-infection

Interventions: Drug: Linezolid
Drug: Standard of Care anti-tuberculous therapy
Drug: High dose rifampicin
Drug: Dexamethasone
Drug: Aspirin

First Posted Date: 2019-04-25

Last Posted Date: 2021-09-28

Lead Sponsor: University of Cape Town

Target Recruit Count: 52

Registration Number: NCT03927313

Locations: 🇿🇦
Mitchells Plain Hospital, Cape Town, Western Cape, South Africa
🇿🇦
Livingstone Hospital, Port Elizabeth, Eastern Cape, South Africa
🇿🇦
New Somerset Hospital, Cape Town, Western Cape, South Africa

and more 1 locations

Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol

Not Applicable

Completed

Conditions: Metabolic Syndrome
Non-Compliance, Medication
Hypertension

Interventions: Drug: Antihypertensive medication according to the study's algorithm

First Posted Date: 2019-04-19

Last Posted Date: 2020-04-28

Lead Sponsor: University of Cape Town

Target Recruit Count: 106

Registration Number: NCT03921086

Locations: 🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa
🇿🇦
George Hospital, George, Western Cape, South Africa
🇿🇦
Somerset Hospital, Cape Town, Western Cape, South Africa

and more 4 locations

Enhanced Recovery After Trauma Surgery

Not Applicable

Active, not recruiting

Conditions: Penetrating Abdominal Trauma

Interventions: Other: Enhanced Recovery Measures

First Posted Date: 2019-04-18

Last Posted Date: 2022-12-09

Lead Sponsor: University of Cape Town

Target Recruit Count: 102

Registration Number: NCT03920163

Locations: 🇿🇦
Groote Schuur Hospital, Cape Town, Western Vape, South Africa

Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers

Phase 1

Terminated

Conditions: HIV Infections

Interventions: Drug: Darunavir/ritonavir 800/100 mg tablet
Drug: Rifampicin 600mg QD tablet and DTG 50mg BD

First Posted Date: 2019-03-27

Last Posted Date: 2019-04-03

Lead Sponsor: University of Cape Town

Target Recruit Count: 17

Registration Number: NCT03892161

Locations: 🇿🇦
Clinical Research Centre, Cape Town, Western Cape, South Africa

A Snapshot Study of Patients Affected by Gunshot Related Injuries in Trauma in South Africa

Completed

Conditions: Gun Shot Wound
Trauma, Multiple

Interventions: Other: No intervention

First Posted Date: 2019-02-26

Last Posted Date: 2021-04-28

Lead Sponsor: University of Cape Town

Target Recruit Count: 138

Registration Number: NCT03854591

Locations: 🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa

African Surgical OutcomeS-2 (ASOS-2) Trial

Not Applicable

Completed

Conditions: Surgery
Morality

Interventions: Other: Increased postoperative surveillance
Other: Usual postoperative care

First Posted Date: 2019-02-26

Last Posted Date: 2020-09-10

Lead Sponsor: University of Cape Town

Target Recruit Count: 27507

Registration Number: NCT03853824

Locations: 🇿🇦
Groote Schuur Hospital, Cape Town, Western Cape, South Africa

Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis

Phase 2

Completed

Conditions: HIV Infections
Tuberculosis

Interventions: Other: Placebo
Drug: Dolutegravir 50 mg

First Posted Date: 2019-02-22

Last Posted Date: 2024-07-18

Lead Sponsor: University of Cape Town

Target Recruit Count: 108

Registration Number: NCT03851588

Locations: 🇿🇦
Khayelitsha Site B/Ubuntu Clinic, Cape Town, Western Cape, South Africa

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