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BeiGene Ltd.

BeiGene Ltd. logo
🇨🇳China
Ownership
Public
Established
2010-01-01
Employees
10K
Market Cap
$22.1B
Website
http://www.beigene.com

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

Phase 3
Recruiting
Conditions
Urothelial Carcinoma
Interventions
First Posted Date
2019-05-30
Last Posted Date
2025-05-02
Lead Sponsor
BeiGene
Target Recruit Count
420
Registration Number
NCT03967977
Locations
🇨🇳

Chinese Pla General Hospital, Beijing, Beijing, China

🇨🇳

The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China

🇨🇳

The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China

and more 43 locations

A Study to Investigate Tislelizumab (BGB-A317) Versus Placebo in Combination With Concurrent Chemoradiotherapy in Participants With Localized Esophageal Squamous Cell Carcinoma

Phase 3
Completed
Conditions
Esophageal Squamous Cell Carcinoma (ESCC)
Interventions
Drug: Placebo
Radiation: Radiotherapy
First Posted Date
2019-05-21
Last Posted Date
2025-05-02
Lead Sponsor
BeiGene
Target Recruit Count
370
Registration Number
NCT03957590
Locations
🇨🇳

The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China

🇨🇳

The First Affiliated Hospitalschool of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China

🇨🇳

Jieyang Peoples Hospital (Jieyang Affiliated Hospital, Sun Yat Sen University ), Jieyang, Guangdong, China

and more 30 locations

A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer

Phase 1
Completed
Conditions
Carcinoma, Hepatocellular
Gastric/Gastroesophageal Junction Cancer
Interventions
First Posted Date
2019-05-08
Last Posted Date
2024-10-26
Lead Sponsor
BeiGene
Target Recruit Count
111
Registration Number
NCT03941873
Locations
🇨🇳

Sun Yat Sen Memorial Hospital, Sun Yat Sen University (North), Guangzhou, Guangdong, China

🇨🇳

Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China

🇨🇳

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

and more 15 locations

Tislelizumab Combined With Chemotherapy Versus Chemotherapy Alone in Recurrent or Metastatic Nasopharyngeal Cancer (NPC)

Phase 3
Completed
Conditions
Recurrent or Metastatic Nasopharyngeal Cancer
Interventions
First Posted Date
2019-04-23
Last Posted Date
2025-01-31
Lead Sponsor
BeiGene
Target Recruit Count
263
Registration Number
NCT03924986
Locations
🇨🇳

Anhui Provincial Hospital, Hefei, Anhui, China

🇨🇳

Chongqing Cancer Hospital, Chongqing, Chongqing, China

🇨🇳

Fujian Cancer Hospital, Fuzhou, Fujian, China

and more 34 locations

Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors

Phase 1
Active, not recruiting
Conditions
Solid Tumor, Adult
Interventions
First Posted Date
2019-04-05
Last Posted Date
2025-03-14
Lead Sponsor
BeiGene
Target Recruit Count
93
Registration Number
NCT03905148
Locations
🇺🇸

University of California Los Angeles, Santa Monica, California, United States

🇺🇸

MD Anderson, Houston, Texas, United States

🇦🇺

Blacktown Cancer and Haematology Centre, Blacktown, New South Wales, Australia

and more 3 locations

Study of Zanubrutinib (BGB-3111) in Participants With Marginal Zone Lymphoma

Phase 2
Completed
Conditions
MZL
Marginal Zone Lymphoma
Interventions
First Posted Date
2019-02-19
Last Posted Date
2024-10-26
Lead Sponsor
BeiGene
Target Recruit Count
68
Registration Number
NCT03846427
Locations
🇺🇸

Clinical Research Alliance, Inc, Westbury, New York, United States

🇺🇸

The Charlotte Mecklenburg Hospital Authority, Charlotte, North Carolina, United States

🇦🇺

The Saint George Hospital Kogarah, Kogarah, New South Wales, Australia

and more 28 locations

A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Phase 3
Completed
Conditions
Esophageal Squamous Cell Carcinoma (ESCC)
Interventions
First Posted Date
2018-12-21
Last Posted Date
2024-10-26
Lead Sponsor
BeiGene
Target Recruit Count
649
Registration Number
NCT03783442
Locations
🇨🇳

Anhui Provincial Cancer Hospital, Hefei, Anhui, China

🇨🇳

Anhui Medical University - The Second Hospital, Hefei, Anhui, China

🇨🇳

Xiangyang Central Hospital, Xiangyang, Hubei, China

and more 173 locations

Tislelizumab in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Gastric, or Gastroesophageal Junction Carcinoma

Phase 3
Completed
Conditions
Gastric, or Gastroesophageal Junction Adenocarcinoma
Interventions
First Posted Date
2018-12-17
Last Posted Date
2025-03-25
Lead Sponsor
BeiGene
Target Recruit Count
997
Registration Number
NCT03777657
Locations
🇨🇳

Foshan First Peoples Hospital, Foshan, Guangdong, China

🇨🇳

Sun Yat Sen University Cancer Center, Guangzhou, Guangdong, China

🇨🇳

Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong, China

and more 146 locations

Study of BGB-A425 and LBL-007 in Combination With Tislelizumab in Advanced Solid Tumors

Phase 1
Completed
Conditions
Locally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2
Interventions
First Posted Date
2018-11-16
Last Posted Date
2025-02-14
Lead Sponsor
BeiGene
Target Recruit Count
114
Registration Number
NCT03744468
Locations
🇺🇸

Chao Family Comprehensive Cancer Center, Orange, California, United States

🇺🇸

University of Colorado Cancer Center, Aurora, Colorado, United States

🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

and more 39 locations

Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors

Phase 2
Recruiting
Conditions
MSI-H/dMMR Solid Tumors
Interventions
First Posted Date
2018-11-09
Last Posted Date
2024-12-06
Lead Sponsor
BeiGene
Target Recruit Count
200
Registration Number
NCT03736889
Locations
🇨🇳

Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Beijing, China

🇨🇳

The Affiliated Hospital of Military Medical Sciences, Beijing, Beijing, China

🇨🇳

Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong, China

and more 26 locations
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