MedPath

BeiGene Ltd.

BeiGene Ltd. logo
🇨🇳China
Ownership
Public
Established
2010-01-01
Employees
10K
Market Cap
$22.1B
Website
http://www.beigene.com

Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader

Phase 1
Recruiting
Conditions
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Waldenström Macroglobulinemia
Follicular Lymphoma
Non-Hodgkin Lymphoma
Marginal Zone Lymphoma
Mantle Cell Lymphoma
B-cell Malignancy
Richter's Transformation
DLBCL Unclassifiable
Interventions
First Posted Date
2022-03-24
Last Posted Date
2025-04-20
Lead Sponsor
BeiGene
Target Recruit Count
146
Registration Number
NCT05294731
Locations
🇨🇳

The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China

🇨🇳

Anhui Provincial Hospital, Hefei, Anhui, China

🇨🇳

Peking University Third Hospital, Beijing, Beijing, China

and more 26 locations

Treatment of Relapsed or Refractory Diffuse Large B Cell Lymphoma With Ociperlimab (BGB A1217) in Combination With Tislelizumab (BGB A317) or Rituximab

Phase 1
Completed
Conditions
Relapsed Diffuse Large B-cell Lymphoma
Refractory Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2022-03-04
Last Posted Date
2024-12-27
Lead Sponsor
BeiGene
Target Recruit Count
53
Registration Number
NCT05267054
Locations
🇨🇳

Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China

🇨🇳

Hunan Cancer Hospital, Changsha, Hunan, China

🇨🇳

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

and more 16 locations

Efficacy and Safety of Tislelizumab (BGB-A317) as Neo-Adjuvant Treatment in Patients With Colorectal Cancer

Phase 2
Completed
Conditions
Colorectal Cancer
Interventions
First Posted Date
2021-11-10
Last Posted Date
2025-03-13
Lead Sponsor
BeiGene
Target Recruit Count
33
Registration Number
NCT05116085
Locations
🇨🇳

The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China

🇨🇳

The Affiliated Hospital of Qingdao University Branch South, Qingdao, Shandong, China

🇨🇳

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China

and more 5 locations

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Phase 3
Recruiting
Conditions
Relapsed/Refractory Follicular Lymphoma
Marginal Zone Lymphoma
Interventions
First Posted Date
2021-10-29
Last Posted Date
2025-06-24
Lead Sponsor
BeiGene
Target Recruit Count
780
Registration Number
NCT05100862
Locations
🇺🇸

Ucsf Fresno University of California San Francisco Fresno, Fresno, California, United States

🇺🇸

Kaiser Permanente Southern California, Irvine, California, United States

🇺🇸

Cancer and Blood Specialty Clinic, Los Alamitos, California, United States

and more 286 locations

First-in-Human, Single- and Multiple-Ascending Dose and Food-Effect Study of BGB-23339 in Healthy Participants

Phase 1
Completed
Conditions
Not Determined
Interventions
Drug: Placebo
First Posted Date
2021-10-26
Last Posted Date
2024-10-23
Lead Sponsor
BeiGene
Target Recruit Count
92
Registration Number
NCT05093270
Locations
🇦🇺

Q PHARM, Herston, Queensland, Australia

🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

🇨🇳

The Affiliated Hospital of Qingdao University Branch West Coast, Qingdao, Shandong, China

Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib

Phase 2
Active, not recruiting
Conditions
Relapsed Diffuse Large B-cell Lymphoma
Refractory Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2021-10-05
Last Posted Date
2025-04-16
Lead Sponsor
BeiGene
Target Recruit Count
66
Registration Number
NCT05068440
Locations
🇨🇳

Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital, Hefei, Anhui, China

🇨🇳

Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing, China

🇨🇳

Fujian Cancer Hospital, Fuzhou, Fujian, China

and more 22 locations

To Evaluate the Efficacy and Safety of Tislelizumab in Combination With Lenvatinib in Patients With Selected Solid Tumors

Phase 2
Completed
Conditions
Advanced Solid Tumor
Interventions
First Posted Date
2021-08-20
Last Posted Date
2024-11-28
Lead Sponsor
BeiGene
Target Recruit Count
58
Registration Number
NCT05014828
Locations
🇨🇳

The Second Hospital of Anhui Medical Hospital, Hefei, Anhui, China

🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

🇨🇳

Beijing Luhe Hospital, Beijing, Beijing, China

and more 13 locations

Ociperlimab With Tislelizumab and Chemotherapy in Participants With Untreated Metastatic Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Locally Advanced, Unresectable, or Metastatic Nonsmall Cell Lung Cancer (NSCLC)
Nonsmall Cell Lung Cancer, Stage IV
Interventions
Drug: histology-based chemotherapy
Drug: Placebo
First Posted Date
2021-08-20
Last Posted Date
2024-12-06
Lead Sponsor
BeiGene
Target Recruit Count
272
Registration Number
NCT05014815
Locations
🇺🇸

Valkyrie Clinical Trials, Los Angeles, California, United States

🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

🇺🇸

Comprehensive Cancer Center of Nevada, Henderson, Nevada, United States

and more 73 locations

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Phase 1
Recruiting
Conditions
Marginal Zone Lymphoma
Chronic Lymphocytic Leukemia
Diffuse Large B Cell Lymphoma
B-cell Malignancy
Small Lymphocytic Lymphoma
Follicular Lymphoma
Waldenström Macroglobulinemia
Non-Hodgkin Lymphoma
Mantle Cell Lymphoma
Interventions
First Posted Date
2021-08-16
Last Posted Date
2025-06-24
Lead Sponsor
BeiGene
Target Recruit Count
621
Registration Number
NCT05006716
Locations
🇺🇸

University of Alabama At Birmingham Hospital, Birmingham, Alabama, United States

🇺🇸

Western Regional Medical Center, Llc, Goodyear, Arizona, United States

🇺🇸

Mayo Clinic Phoenix, Phoenix, Arizona, United States

and more 114 locations

Study of Tislelizumab in Participants With Resectable Esophageal Squamous Cell Carcinoma

Phase 2
Completed
Conditions
Resectable Esophageal Squamous Cell Carcinoma
Interventions
First Posted Date
2021-07-23
Last Posted Date
2024-11-27
Lead Sponsor
BeiGene
Target Recruit Count
70
Registration Number
NCT04974047
Locations
🇨🇳

The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China

🇨🇳

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

🇨🇳

West China Hospital, Sichuan University, Chengdu, Sichuan, China

and more 5 locations
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