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Clinical Trials
38
4 active
Approvals
0
Total approvals
Agencies
Regulatory bodies
Founded
1881
Active, not recruiting
2
5.3%
Completed
17
44.7%
Not yet recruiting
Recruiting
9
23.7%
Unknown
8
21.1%
No approval data available
- A University of Nottingham-led study published in BMC Biology identifies the lemon frost leopard gecko as a novel animal model for studying cancer, with tumors appearing naturally in approximately 80% of individuals. - Whole-genome sequencing revealed recurring genetic changes in gecko tumors that affect the same genes and biological pathways implicated in human cancers. - Unlike laboratory mice that require tumor induction, lemon frost geckos develop aggressive, metastatic tumors at a relatively young age, offering a rare window into natural cancer progression. - Researchers emphasize that studying species across the tree of life, including cancer-susceptible and cancer-resistant animals, could inspire new strategies for cancer prevention, detection, and treatment in humans.
