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Efficacy and Safety of BMSCs (CG-BM1) for ACLF Patients

Phase 1
Recruiting
Conditions
Acute-On-Chronic Liver Failure
Interventions
Drug: Solvent of CG-BM1
Drug: Bone marrow mesenchymal stem cells (low dose)
Drug: Bone marrow mesenchymal stem cells (medium dose)
Drug: Bone marrow mesenchymal stem cells (high dose)
First Posted Date
2024-12-18
Last Posted Date
2024-12-18
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
90
Registration Number
NCT06740149
Locations
🇨🇳

Third Affliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Daily Versus Alternate Day Plasma Exchange in Wilson Disease With Acute Liver Failure in Children

Not Applicable
Not yet recruiting
Conditions
Acute Liver Failure
Wilson Disease
Interventions
Biological: Plasma Exchange
Other: Standard Medical Treatment
First Posted Date
2024-11-21
Last Posted Date
2024-11-21
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
20
Registration Number
NCT06698991
Locations
🇮🇳

Institute of Liver & Biliary Sciences, New Delhi, Delhi, India

Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With HBV-ACLF and Sepsis

Not Applicable
Recruiting
Conditions
Sepsis
Acute-On-Chronic Liver Failure
Interventions
Device: double plasma cytokine adsorption system with sequential low-dose plasma exchange
Other: plasma exchange
First Posted Date
2024-08-20
Last Posted Date
2024-11-28
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
60
Registration Number
NCT06562803
Locations
🇨🇳

Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Safety and Efficacy of Continuous Infusion of Terlipressin With Norepinephrine Versus Norepinephrine Alone in Improving Outcomes of Acute Kidney Injury in Acute on Chronic Liver Failure With Septic Shock

Not Applicable
Not yet recruiting
Conditions
Acute on Chronic Liver Failure
Interventions
Drug: Terlipressin
Drug: Norephrine
First Posted Date
2024-08-16
Last Posted Date
2024-08-16
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
126
Registration Number
NCT06556472
Locations
🇮🇳

Institute of Liver & Biliary Sciences (ILBS), New Delhi, Delhi, India

High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema

Not Applicable
Not yet recruiting
Conditions
Cerebral Edema
Acute Liver Failure
Interventions
Procedure: High Volume Therapeutic Plasma Exchange compared to standard volume therapeutic plasma exchange
First Posted Date
2024-07-23
Last Posted Date
2024-12-11
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
60
Registration Number
NCT06515145
Locations
🇮🇳

Institute of Liver & Biliary Sciences, New Delhi, Delhi, India

Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection

Recruiting
Conditions
Acute-On-Chronic Liver Failure
First Posted Date
2024-05-31
Last Posted Date
2024-05-31
Lead Sponsor
Qin Ning
Target Recruit Count
400
Registration Number
NCT06437067
Locations
🇨🇳

Department of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.

Not yet recruiting
Conditions
Acute-On-Chronic Liver Failure
Interventions
First Posted Date
2024-04-26
Last Posted Date
2024-04-26
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
480
Registration Number
NCT06387160
Locations
🇮🇳

Institute of liver and Biliary Sciences, New Delhi, Delhi, India

To Optimize Therapeutic Procedures of DPMAS in ACLF Patients: a Prospective, Sigle Arm and Multicenter Study

Not yet recruiting
Conditions
Acute-On-Chronic Liver Failure
Interventions
Other: No intervention in this study
First Posted Date
2024-04-22
Last Posted Date
2024-04-22
Lead Sponsor
Nanfang Hospital, Southern Medical University
Target Recruit Count
2000
Registration Number
NCT06377774

Feasibility Pilot Study to Evaluate the Safety and Performance of the MEX-CD1 Medical Device in ACLF

Not Applicable
Recruiting
Conditions
Acute on Chronic Liver Failure
Multiple Organ Failure
Interventions
Device: MEX-CD1 Dialysis
First Posted Date
2024-04-01
Last Posted Date
2024-08-21
Lead Sponsor
Mexbrain
Target Recruit Count
10
Registration Number
NCT06340269
Locations
🇫🇷

Hôpital Croix Rousse, Service d'hépatologie et gastroentérologie, Lyon, Rhône-Alpes, France

Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF Patients

Not yet recruiting
Conditions
Acute-On-Chronic Liver Failure
First Posted Date
2024-03-07
Last Posted Date
2024-03-07
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
100
Registration Number
NCT06298656
Locations
🇮🇳

Institute of Liver & Biliary Sciences (ILBS), New Delhi, Delhi, India

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