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Found 6 clinical trials|View Analysis
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Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:

Phase 2
Recruiting
Conditions
Pharmacogenomic Drug Interaction
Side Effect of Drug
Drug Metabolism, Poor, CYP2D6-Related
Ineffective Drug Action
Drug Metabolism, Poor, CYP2C19-Related
Interventions
Diagnostic Test: PGx panel test
First Posted Date
2024-03-21
Last Posted Date
2024-12-11
Lead Sponsor
Mayo Clinic
Target Recruit Count
66
Registration Number
NCT06322238
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Assessment of Methadone Dose Taken Using Electrochemistry

Conditions
Methadone Overdose
Drug Metabolism, Poor, CYP2D6-Related
Methadone Toxicity
Pain, Chronic
Metabolism Medication Toxicity
Interventions
Device: ISF extraction device 1
Diagnostic Test: Measurement of Methadone in the Interstitial Fluid (ISF) before and after prescribed dose taken ex vivo
Device: Measurement of Methadone in the Interstitial Fluid before and after prescribed dose taken in vivo
Drug: Measurement of Methadone in ISF before and after taking prescribed dose
Device: ISF Extraction Device 2
First Posted Date
2023-08-08
Last Posted Date
2024-08-22
Lead Sponsor
Cari Health Inc.
Target Recruit Count
30
Registration Number
NCT05981573
Locations
🇺🇸

Synergy, Lemon Grove, California, United States

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Not Applicable
Completed
Conditions
CYP2D6 Polymorphism
Cytochrome P450 CYP2C9 Enzyme Deficiency
Drug Metabolism, Poor, CYP2D6-RELATED
Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Drug Metabolism, Poor, CYP2C19-RELATED
Ultrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Extensive Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Cytochrome P450 CYP2D6 Enzyme Deficiency
Cytochrome P450 CYP2C19 Enzyme Deficiency
Interventions
Genetic: Pharmacogenetic testing
Other: Software-based drug & gene interaction risk analysis
Other: MTM
First Posted Date
2015-04-29
Last Posted Date
2017-02-23
Lead Sponsor
Genelex Corporation
Target Recruit Count
341
Registration Number
NCT02428660
Locations
🇺🇸

VRx Pharmacy Services, Salt Lake City, Utah, United States

Pharmacogenetic Testing Among Home Health Patients

Not Applicable
Completed
Conditions
Adverse Drug Reactions
Cytochrome P450 CYP2D6 Enzyme Deficiency
Cytochrome P450 CYP2C19 Enzyme Deficiency
Cytochrome P450 CYP3A Enzyme Deficiency
Adverse Drug Events
Drug Metabolism, Poor, CYP2D6-RELATED
Cytochrome P450 Enzyme Deficiency
Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant
Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Drug Interaction Potentiation
Interventions
Genetic: Pharmacogenetic testing
First Posted Date
2015-03-04
Last Posted Date
2019-09-20
Lead Sponsor
Genelex Corporation
Target Recruit Count
110
Registration Number
NCT02378220
Locations
🇺🇸

White County Medical Center Home Health, Searcy, Arkansas, United States

YouScript IMPACT Registry

Completed
Conditions
Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Adverse Drug Reactions
Poor Metabolizer Due to Cytochrome P450 CYP2C19 Variant
Drug Interaction Potentiation
Drug Metabolism, Poor, CYP2C19-RELATED
Cytochrome P450 CYP2D6 Enzyme Deficiency
Cytochrome P450 CYP2C9 Enzyme Deficiency
Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant
Cytochrome P450 Enzyme Deficiency
Cytochrome P450 CYP3A Enzyme Deficiency
First Posted Date
2014-07-16
Last Posted Date
2017-03-01
Lead Sponsor
Genelex Corporation
Target Recruit Count
800
Registration Number
NCT02191358
Locations
🇺🇸

Dr. Michael Dao, Garden Grove, California, United States

🇺🇸

Kaiser Permanente Colorado, Denver, Colorado, United States

🇺🇸

Gill Heart Institute, Lexington, Kentucky, United States

and more 4 locations

Pharmacogenetic Factors and Side Effects of Metoclopramide and Diphenhydramine

Phase 1
Terminated
Conditions
Drug Metabolism, Poor, CYP2D6-RELATED
Interventions
First Posted Date
2011-02-04
Last Posted Date
2016-05-13
Lead Sponsor
Matthias Schwab
Target Recruit Count
49
Registration Number
NCT01289938
Locations
🇩🇪

Abteilung Klinische Pharmakologie, UKT Tübingen, Tübingen, BW, Germany

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