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Found 2 clinical trials|View Analysis
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Donor-Alloantigen-Reactive Regulatory T Cell (darTreg) Therapy in Renal Transplantation (The ONE Study )

Phase 1
Completed
Conditions
Kidney Disease
Interventions
Drug: darTreg infusion
First Posted Date
2014-09-19
Last Posted Date
2018-10-15
Lead Sponsor
University of California, San Francisco
Target Recruit Count
6
Registration Number
NCT02244801
Locations
🇺🇸

University of California San Francisco - Transplant Department. 513 Parnassus Ave HSE 504, San Francisco, California, United States

Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation

Phase 1
Terminated
Conditions
Liver Transplantation
Interventions
Biological: Anti-Thymocyte Globulin - Rabbit
Biological: darTreg Infusion
Drug: Everolimus
Drug: Tacrolimus
Drug: Mycophenolate mofetil
Drug: Anti-Infective Prophylaxis
Drug: Prednisone
Procedure: Blood draws
Drug: Acetaminophen
Procedure: Liver biopsies
Drug: Diphenhydramine
Procedure: Liver transplantation
Procedure: Leukapheresis
First Posted Date
2014-07-14
Last Posted Date
2020-09-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
15
Registration Number
NCT02188719
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

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