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Found 4013 clinical trials|View Analysis
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Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)

Phase 1
Not yet recruiting
Conditions
Advanced Solid Malignancies
Interventions
Drug: Tiragolumab
Drug: Atezolizumab
Radiation: Radiation Therapy
First Posted Date
2025-01-06
Last Posted Date
2025-01-06
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
56
Registration Number
NCT06760481
Locations
🇺🇸

The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Phase 2
Recruiting
Conditions
Rectal Cancer
Total Neoadjuvant Treatment
Neoadjuvant Therapy
Radiotherapy
Chemotherapy
Organ Preservation
Radiotherapy Side Effect
Chemotherapy Side Effects
Chemoradiotherapy
Low Anterior Resection Syndrome
Interventions
Radiation: Radiation Therapy
Other: Part two
Drug: Chemoradiotherapy
Other: Adjuvant treatment
Drug: Consolidation Chemotherapy
Procedure: Surgery
First Posted Date
2025-01-06
Last Posted Date
2025-01-09
Lead Sponsor
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Target Recruit Count
400
Registration Number
NCT06758830
Locations
🇱🇹

Nacional Cancer Institute, Vilnius, Lithuania

Low-Level Laser Therapy and Injectable Platelet-Rich Fibrin for Thin Gingival Phenotype.

Phase 3
Completed
Conditions
Periodontal Diseases
Interventions
Other: injecable platelet rich fibrin, and low level laser therapy radiation.
First Posted Date
2025-01-03
Last Posted Date
2025-01-03
Lead Sponsor
Faculty of Dental Medicine for Girls
Target Recruit Count
7
Registration Number
NCT06756854
Locations
🇪🇬

Alaa Elsayed, Cairo, Egypt

Personalized Cancer Vaccines Combined with Radiation Therapy.

Early Phase 1
Not yet recruiting
Conditions
Breast Cancer, Colorectal Cancer
Melanoma
Lung Cancer
Interventions
Biological: individualized tumor FAST vaccine combination (including adjuvant)
First Posted Date
2025-01-01
Last Posted Date
2025-01-08
Lead Sponsor
Fengming Kong
Target Recruit Count
154
Registration Number
NCT06756295

Dosimetric Comparison of Target Volume, Heart and Left Lung in Post Mastectomy Radiotherapy (RT) of Left Sided Breast Cancer by Free Breathing (FB) Versus Deep Inspiration Breath Hold (DIBH) Technique

Not Applicable
Active, not recruiting
Conditions
Carcinoma Breast
Radiation Therapy for Primary Breast Cancer
Radiation Tolerance
Radiation Induced Cardiac Damage
Radiation Induced Lung Injury (RILI)
Radiotherapy; Adverse Effect
Radiotherapy, Adjuvant
First Posted Date
2024-12-24
Last Posted Date
2024-12-24
Lead Sponsor
Nishat Tasnim
Target Recruit Count
50
Registration Number
NCT06746142
Locations
🇧🇩

Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

🇧🇩

Combined Military Hospital, Dhaka, Dhaka, Bangladesh

🇧🇩

Delta Hospital Limited, Dhaka, Dhaka, Bangladesh

and more 1 locations

Activity Coaching During Pelvic Radiation Therapy

Not Applicable
Not yet recruiting
Conditions
Radiation Therapy
Gynecologic Cancer
Exercise Therapy
First Posted Date
2024-12-24
Last Posted Date
2024-12-24
Lead Sponsor
Inova Health Care Services
Target Recruit Count
16
Registration Number
NCT06746428
Locations
🇺🇸

Inova Schar Cancer Institute, Fairfax, Virginia, United States

Comparing Radiation Therapy to Usual Care for Patients With High-Risk Bone Asymptomatic Metastases

Phase 3
Not yet recruiting
Conditions
Metastatic Malignant Neoplasm in the Bone
Metastatic Malignant Solid Neoplasm
First Posted Date
2024-12-20
Last Posted Date
2024-12-20
Lead Sponsor
NRG Oncology
Target Recruit Count
280
Registration Number
NCT06745024

Preoperative Radiation Therapy and Immediate Breast Reconstruction

Not Applicable
Not yet recruiting
Conditions
Breast Neoplasms
Breast Carcinoma
Breast Adenocarcinoma
Cancer
Neoplasm
First Posted Date
2024-12-18
Last Posted Date
2024-12-18
Lead Sponsor
Cancer Research Antwerp
Target Recruit Count
180
Registration Number
NCT06739655
Locations
🇧🇪

Ziekenhuis aan de stroom, Wilrijk, Antwerpen, Belgium

A Phase II, Single-arm, Single-centre Trial to Evaluate the Efficacy and Safety of Nalusobasumab in Combination with Stereotactic Radiosurgery to Improve the Efficacy of First-line Chemotherapy Combined with Immunotherapy in Patients with Bone Metastases from Advanced Non-small Cell Lung Cancer

Phase 2
Not yet recruiting
Conditions
NSCLC
Stereotactic Body Radiation Therapy (SBRT)
Immunotherapy
Interventions
Drug: nalusobasumab
First Posted Date
2024-12-17
Last Posted Date
2024-12-17
Lead Sponsor
Fudan University
Target Recruit Count
27
Registration Number
NCT06738160

Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy

Phase 4
Recruiting
Conditions
Trismus
Head and Neck Cancer
Radiation Therapy Recipient
BOTOX
Interventions
Drug: Echo-guided Botox injection
Procedure: echo-guided normal saline injection
First Posted Date
2024-12-16
Last Posted Date
2024-12-16
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
120
Registration Number
NCT06734598
Locations
🇨🇳

National Taiwan University Hospital, Taipei City, Taiwan

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