Low-Level Laser Therapy and Injectable Platelet-Rich Fibrin for Thin Gingival Phenotype.

Phase 3

Completed

• Conditions: Periodontal Diseases
• Interventions: Other: injecable platelet rich fibrin, and low level laser therapy radiation.

• Registration Number: NCT06756854
• Lead Sponsor: Faculty of Dental Medicine for Girls

Brief Summary

Management of thin gingival phenotype using non-surgical methods (injection of liquid platelet rich fibrin and exposure to low level laser therapy

Detailed Description

Thin gingival phenotype can lead to recession and root exposure. Liquid prf can be obtained by centrifugion of blood sample on speed 700 rpm for 3 min, then injection of this liquid in the attached gingiva and muco-gingival junction (3 times with 7 days interval) for the first group. The second group will be injected with I-PRF in the same method in addition to exposure to Low Level Laser therapy (after each injection of I-PRF). This method is expected to increase the thickness of the gingiva.

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study Start: 2023-09-12
• Primary Completion: 2024-05-14
• Study Completion: 2024-06-15
• Study First Submitted: 2024-06-21
• Status Verified: 2024-12
• Study First Submitted QC: 2024-12-25
• Last Update Submitted: 2024-12-25
• Study First Posted: 2025-01-03
• Last Update Posted: 2025-01-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 7

Inclusion Criteria

• free systimatically good oral hygiene gingival thickness less than 1mm

Read More

Exclusion Criteria

• pregnancy or lactation pereiodontitis periodontal surgery orthodontic ttt tooth mobility,bruxism,crowding,missing or supernumerary teeth smoking

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Test group: injectable platelet rich fibrin+ low level laser therapy	injecable platelet rich fibrin, and low level laser therapy radiation.	patients with thin gingival phenotype (gingival thickness less than 1mm) recieve I-PRF+LLLT radiation just after the injection for 3 sessions with 7 days interval between the sessions.

Primary Outcome Measures

Name	Time	Method
Gingival thickness improvement in millimeters.	6 months after treatment	clinical parameter
Keratinized tissue width improvement in millimeters.	6 months after treatment	Clinincal parameter.

Secondary Outcome Measures

Name	Time	Method
Improvement of gingival index.	6 months after treatment	Clinical parameter.
Improvement of bleeding on probing.	6 months after treatment	Clinical parameter.
Improvement of sulcus depth.	6 months after treatment	Clinical parameter.

Trial Locations

Locations (1)

Alaa Elsayed; 🇪🇬 Cairo, Egypt