Control Cohort CTRL COH
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Samples (blood dry and EDTA tube and optional cerebro-spinal-fluid)
研究概览
简要总结
Autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS) are rare disease that could be difficult to diagnose. So it necessary to obtain numerous sample from different disease to develop more specific diagnosis kit It could be possible through the characterisation of new genetic biomarkers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with consent
- •patient with following disease: Parkinson's disease, Amyotrophic lateral sclerosis, Glioblastoma, cancer without neurological disease (pulmonary cancer, breast cancer, ovarian cancer, melanoma, thymoma), rheumatoid arthritis.
排除标准
- •refusal consent
- •patient with neurological disorder compatible with paraneoplastic neurological syndrome or auto-immune encephalitis
- •patient under guardianship
研究组 & 干预措施
Control cohort
Patient with following disease: Parkinson's disease, Amyotrophic lateral sclerosis, Glioblastoma, cancer without neurological disease (pulmonary cancer, breast cancer, ovarian cancer, melanoma, thymoma), rheumatoid arthritis.
干预措施: Collection of biological sample (blood and/or CSF) (Biological)
结局指标
主要结局
Samples (blood dry and EDTA tube and optional cerebro-spinal-fluid)
时间窗: 15 minutes
Numbers of samples collected and patients included in the cohort
次要结局
- Description of genetic analysis(Data collecting: 3 years Data analysis: 2 years)