Intensive Attention Training to Treat Brain Fog in Individuals With Long-Covid
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Number of participants who successfully completed at least 80% of the study tasks sessions
研究概览
简要总结
This study is to find out if the Attention Processing Training program is a potential treatment for brain fog symptoms, reported by people with Long-Covid. Also investigating the feasibility of completing this program virtually.
详细描述
The goal of this project is to test the feasibility, acceptability and efficacy of an attention training intervention (Attention Process Training; APT-3) as a potential treatment for brain fog symptoms experienced by people with Long-Covid. There already is good empirical evidence to support the idea that the APT-3 treatment is feasible and effective in improving attention in people with acquired brain injuries, but information about its efficacy and acceptability in people with Long-Covid brain fog is lacking.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18-65 years.
- •A history of confirmed SARS-CoV-2 infection.
- •Subjective reports of cognitive symptoms that interfere with everyday activities, starting on or shortly after SARS-CoV-2 infection.
- •Continuation or development of Long-Covid brain fog 3 months after the initial SARS-CoV-2 infection, with these symptoms lasting for at least 2 months with no other explanation.
- •Objective attentional deficits as measured by the Conners CPT-312, and/or the Digit Span subtest (WAIS- III13).
- •Able to use a keyboard.
- •Able to understand and communicate in English.
- •Able to consent independently.
排除标准
- •Being hospitalized due to COVID-19 diagnosis for more than 3 days.
- •Pre-morbid neurological conditions that could potentially affect cognition, such as Parkinson's Disease, Alzheimer's Dementia, acquired brain injury.
- •Severe depression.
- •Currently enrolled in cognitive training or physical exercise training.
- •Receiving chemotherapy or radiation within last 6 months.
- •Active substance abuse.
结局指标
主要结局
Number of participants who successfully completed at least 80% of the study tasks sessions
时间窗: 2 years
Recording the number of participants who completed at least 80% of the study sessions out of the number of all participants who enrolled in the study.
次要结局
- Change of scores in objective attention tests (i.e, CPT 3), pre- and post -intervention(2 year)
研究者
Shira Cohen-Zimerman
Principal Investigator
Shirley Ryan AbilityLab