The association between aging or chronic diseases and mitochondrial oxygenation and oxygen consumption as measured with the Protoporphyrin IX Triplet State Lifetime Technique - Aging, chronic disease, mitoPO2 and mitoVO2

Anesthesiologie0 个研究点目标入组 319 人开始时间: 待定最近更新: 2024年4月9日

适应症

试验速览

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•Healthy volunteers
•In order to be eligible to participate in this study, a subject must meet all
•of the following criteria:
•- Aged between 18 years of age and 90 years of age
•- Acceptable proficiency of the Dutch language
•- Healthy volunteers without physical or mental illness
•Comorbidity group
•In order to be eligible to participate in this study, a subject must meet all
•of the following criteria:
•- Aged between 18 years of age and 90 years of age
•- Acceptable proficiency of the Dutch language
•- One of the underlying illnesses: neurodegenerative disease, diabetes mellitus
•type II or obesity (BMI>30), no other relevant comorbidity

•A potential subject who meets any of the following criteria will be excluded
•from participation in this study:
•- Porphyria
•- Known intolerance to components of the ALA plaster
•- Presence of mitochondrial disease
•- Pregnancy/lactation
•- Patients with skin lesions on the measurement location which impede
•measurements
•- Incapability to provide inform consent, due to a mental condition interfering
•with the ability to understand the provided information

发起方

Anesthesiologie