NCT00969891已完成不适用
Population Based Pharmacokinetic and Pharmacodynamic Dosage Model for Cytarabine, Daunorubicin and Etoposide for Acute Myeloid Leukemia
Mikkel Krogh-Madsen2 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2009年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- significant covariates from the PK study
研究概览
简要总结
The present study is not hypothesis driven but will explore the ability of pharmacokinetic-pharmacodynamic modelling to predict optimal dosage of the chemotherapeutic drugs used in therapy in adult patients with acute myeloid leukemia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult men and women with newly diagnosed acute myeloid leukemia
排除标准
- •under age 18 years
结局指标
主要结局
significant covariates from the PK study
时间窗: after complete analysis of data
次要结局
- Amount of the three drugs in patient plasma samples(within 3 months of sampling)
研究者
Mikkel Krogh-Madsen
PhD student
University of Copenhagen
研究点 (2)
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