Impact of Dehydration and Rapid Rehydration on Cognitive Function
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Multitasking test
研究概览
简要总结
The investigators want to understand the impact of the body losing and gaining water on brain function. Participants will restrict fluids consumed and exercise to lose 5% of body mass. Participants will then be provided fluid equal to the volume lost to consume over 2 hours (recovery). A series of brain function tests will be performed at baseline, following weight loss, and following recovery.
详细描述
A baseline series of brain function tests will be performed. Following this, participants will complete a 24 hour fluid and water rich food restriction on the day proceeding testing. Participants will then complete moderate to high intensity exercise in a hot/humid room to achieve 5% body mass loss. Once baseline core body temperature returns to baseline levels, the series of brain function tests will be performed. Participants will then consume a sports drink equal to the volume of sweat lost over the course of a 2 hour recover period. Following this, he series of brain function tests will be performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 26 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Recreationally active
- •18-26 years old
排除标准
- •History of cardiovascular, metabolic, respiratory, neural, or renal disease
- •Hypertensive (systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg) or tachycardic (resting heart rate ≥ 100 bpm) during the screening visit
- •Taking medication or supplements with a known side effect of affecting physiological responses to exercise (e.g., aspirin, acetaminophen, beta blockers, statins, stimulants, depressants, SSRIs)
- •Tobacco or nicotine use in the past six months
- •Current or past musculoskeletal injury impacting physical activity
- •Study physician discretion based on any other medical condition or medication
研究组 & 干预措施
Dehydration and Rehydration Arm
Participants will complete exercise until 5% body mass loss, followed by ad libitum rehydration throughout 2 hours of recovery.
干预措施: Fluid loss and consumption (Behavioral)
结局指标
主要结局
Multitasking test
时间窗: 2 hours following the dehydration cognitive function test, approximately 4.5 hours into the trial
Accuracy score of a multitasking test (0-100%) with greater scores indicating a better outcome
次要结局
未报告次要终点
研究者
Riana Pryor
Assistant Professor
State University of New York at Buffalo