phytoestrogens as an alternative to estradiol in reversing the antiestrogenic effect of clomid in ovulation induction in cases of PCOS

Ahmed Maged0 个研究点目标入组 150 人开始时间: 2014年7月24日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•1. All participants had the diagnosis of polycystic ovarian syndrome (PCOS) based on presence of at least two of the following diagnostic criteria should be met: oligo/anovulation; clinical signs of hyperandrogenism (e.g., hirsutism and acne) and/or biochemical measurements; or enhanced polycystic ovaries and/or multiple discrete follicles in diameter in one ovary as detected by ultrasonography. The criteria fulfilling sufficient specificity and sensitivity to define PCO are the following: `presence of 12 or more follicles in each ovary measuring 2-9 mm in diameter, and/or increased ovarian volume (>10 cm3)
•2. Women with both 1ry and 2ry infertility were included.

•1. women with endocrinological abnormalities as thyroid dysfunction or abnormal prolactin levels,
•2. those with hypothalamic or pituitary dysfunctions evaluated by low gonadotropin level,
•3. other causes of infertility as tubal factor evaluated by HSG or laparoscopy, abnormal uterine cavity evaluated by sonohystrography or hysteroscopy and male factor evaluated by semen analysis.
•4. Women with ovarian cysts were also excluded from the study

发起方

Ahmed Maged