NCT01006473已完成4 期
A Randomized Trial of the Effects of Exercise Training in Chagas Cardiomyopathy
Federal University of Minas Gerais2 个研究点 分布在 1 个国家目标入组 37 人开始时间: 2007年3月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 37
- 试验地点
- 2
- 主要终点
- Health related quality of life
研究概览
简要总结
The benefits of exercise training in heart failure are well established. Its effects, however, have not been evaluated in Chagas cardiomyopathy (ChC). The investigators hypothesis is that the exercise training may improve functional capacity, quality of life (QoL), and reduce brain natriuretic peptide (BNP) levels in patients with ChC.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic Chagas dilated cardiomyopathy, defined by the echocardiography finding of a dilated left ventricle with moderate or severe impaired left ventricular systolic function (left ventricular ejection fraction ≤ 45%).
- •To be clinically stable for at least 3 months
- •To have sinus rhythm
- •To be under standard medical therapy use at the time.
排除标准
- •Inability to attend regular exercise training
- •The presence of a pacemaker, associated cardiac or systemic diseases
- •Practitioners of regular physical activity
结局指标
主要结局
Health related quality of life
时间窗: 12 weeks
Functional class
时间窗: 12 weeks
Functional capacity
时间窗: 12 weeks
BNP levels
时间窗: 12 weeks
次要结局
- Complications related to the exercise training(12 weeks)
研究者
Antonio Luiz Pinho Ribeiro
Professor
Federal University of Minas Gerais
研究点 (2)
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