NCT02832505撤回不适用
Applications of MRI in Kidney Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- MRI measured perfusion for each patient group
研究概览
简要总结
This study has two major purposes:
- To test developed multiple anatomic and functional MRI methods;
- To evaluate the potentials of these MRI methods in the diagnosis, prognosis, and monitoring of the progression of renal dysfunction.
These purposes will be achieved by performing pilot studies with cohorts of patients.
详细描述
This study is observational with no intervention applied for the patients. In this study, multiple anatomic and functional MRI methods will be performed with three cohorts of patients. In addition to anatomic MRI methods, non-contrast enhanced functional MRI methods will also be applied to evaluate tissue perfusion and vascular reactivity in these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •English-speaking as primary language
- •Able to complete an approximately 75 to 90 minute cognitive and/or physical tests
- •Capable to consent to studies
排除标准
- •Acute psychiatric illness that would impede cognitive testing
- •Active chemical dependence, such as alcohol, narcotics or other drugs
- •Legally blind or unable to complete cognitive tests due to visual loss or deafness
- •Renal transplant recipient at time of screening or baseline
- •Severe CI unable to complete the Modified Mini-Mental State Examination [3MSE]
- •Chronic and acute pulmonary disease
结局指标
主要结局
MRI measured perfusion for each patient group
时间窗: Baseline
MRI measurements will be summarized for each patient group by using mean and standard deviation or standard error.
次要结局
未报告次要终点
研究者
研究点 (1)
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