NCT04067154已完成不适用
Does a Bedside Method for Describing Functional Gas Exchange Compare Well With Anatomical Description Via CT Scans, and Could it Predict the Effects of Recruitment and Ventilation/Perfusion Mismatch Improvement
Policlinico Hospital2 个研究点 分布在 1 个国家目标入组 13 人开始时间: 2012年8月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Gas Exchange and lung recruitability at diferent PEEP levels
研究概览
简要总结
The study aims to investigate the association between effects of PEEP on gas exchange model parameters and CT scan results
详细描述
In ARDS patients on mechanical ventilation, we will compare model-based estimation of gas exchange parameters (shunt, ventilation/perfusion mismatch) with CT-based estimation of effects of low and high PEEP
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- ARDS patients requiring mechanical ventilation
排除标准
- •<18 years old
- •Requirement of extracorporal life support
- •Hemodynamic instability
- •Barotrauma
结局指标
主要结局
Gas Exchange and lung recruitability at diferent PEEP levels
时间窗: Approximately two hours
Gas exchange (At PEEP 5 and 20 cm H2O), CT scan (At PEEP 5, 20 and 45 cm H2O)
次要结局
- Physiologic Parameter 1(Approximately two hours)
- Physiologic Parameter 2(Approximately two hours)
研究者
Mauro Panigada
Does a bedside method for describing functional gas exchange compare well with anatomical description via CT scans, and could it predict the effects of recruitment and ventilation/perfusion mismatch improvement.
Policlinico Hospital
研究点 (2)
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