NCT00501423已完成不适用
Antiplatelet Drug Resistances and Ischemic Events
Pierre Fontana1 个研究点 分布在 1 个国家目标入组 771 人开始时间: 2006年6月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 771
- 试验地点
- 1
- 主要终点
- MACE
研究概览
简要总结
The ADRIE study is an observational study on the clinical relevance of platelet reactivity in aspirin and clopidogrel treated cardiovascular patients.
详细描述
The ADRIE study is an observational study on the clinical relevance of platelet reactivity in aspirin and clopidogrel treated cardiovascular patients.
Main objective:
- to determine if platelet reactivity, assessed by specific and non-specific tests, is predictive of ischemic events during the 3-year follow-up.
Secondary objectives:
- primary outcome in each pre-specified sub-group : patients with coronary artery disease, ischemic stroke or peripheral arterial disease as main qualifying disease at entry,
- to determine if platelet reactivity, assessed by specific and non-specific tests, is predictive of bleeding events during the 3-year follow-up,
- to investigate potential determinants of platelet reactivity at entry in the study
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Documented symptomatic ischemic atherothrombotic disease treated by aspirin, clopidogrel or both.
排除标准
- •Known platelet disorder
- •Chronic treatment by antiplatelet drugs other than aspirin or clopidogrel.
- •Chronic anticoagulant treatment
- •Chronic non steroid anti inflammatory drug treatment
- •Active cancer
- •Ongoing aspirin or clopidogrel treatment taken for more than 5 years prior to inclusion
结局指标
主要结局
MACE
时间窗: prospective follow-up
adjudicating committee
次要结局
- MACE in pre-specified sub-groups(prospective follow-up)
研究者
Pierre Fontana
PI
University Hospital, Geneva
研究点 (1)
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