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临床试验/NCT06479993
NCT06479993Unknown不适用

The Influence of Chlorella Supplementation on Running Performance

University College, London1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2024年1月5日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
20
试验地点
1
主要终点
Changes in oxygen consumption and oxygen cost

研究概览

简要总结

Algae, such as chlorella, are gaining popularity as a nutritious additive to whole food or as a supplement. They contain a variety of beneficial nutrients like vitamins, minerals, healthy fats, and amino acids, which can have positive effects on our health and possibly athletic performance. Chlorella, specifically, is a type of single-celled green algae that you can easily find in health stores worldwide. While there's some evidence suggesting that chlorella supplementation might improve submaximal and maximal performance for cyclists, it's unclear if it has the same impact on runners. To investigate this, the investigators aim to conduct a double-blind randomised placebo controlled study to see if taking chlorella daily for 3-weeks can enhance different aspects of running performance, both during low/moderate and intense exercise, among individuals who regularly engage in running.

详细描述

After signing the consent form, we will invite you to come to the ISEH laboratory on Tottenham Court Road so we can take some basic baseline readings. This should last up to 60 minutes and will also include a V̇o2max Test (visit 1). After this, you will be randomly allocated either start on chlorella or placebo first. After supplementation (for visit 2 and 3) you will be required to perform a submaximal running test which will entail running at 60% GET (gas exchange threshold), 80% GET, and 75% of the change from peak. This will then be shortly followed by an incremental test to fatigue.

You will then be required to undergo the exact same supplementation period on the alternative supplement with the same exercise test performed.

You will be required to come into the laboratory a total of 3 times. Each visit should take roughly 1 - 1.5 hours.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Run regularly (3-4 times a week).
  • •Train with a purpose to compete.
  • •Consider running to be your main sport.
  • •Be comfortable running continuously for over 30-minutes at moderate intensity.
  • •Represent a local running club.

排除标准

  • •Individuals taking blood thinners.
  • •Known allergies to algae/mould and iodine.
  • •Any illness/conditions identified on PARQ (please see attached PARQ)
  • •Taking immunosuppressant medication

研究组 & 干预措施

Chlorella supplementation

Experimental

Supplementation of chlorella (6g/day for 3-weeks)

干预措施: Chlorella supplementation (Dietary Supplement)

Placebo supplementation

Placebo Comparator

Supplementation of placebo (6g/day for 3-weeks)

干预措施: Placebo supplementation (Dietary Supplement)

结局指标

主要结局

Changes in oxygen consumption and oxygen cost

时间窗: Following each 3-week supplementation period of either chlorella or placebo

Assessing the possible changes in oxygen consumption and oxygen cost (ml/kg/min) at 60% Gas Exchange threshold (GET), 80% GET, and 75% change as measured by a metabolic cart (Vyntus)

Changes in lactate

时间窗: Following each 3-week supplementation period of either chlorella or placebo

Assessing the possible changes in blood lactate at 60% Gas Exchange threshold (GET), 80% GET, and 75% change, at maximal oxygen uptake, and 15-mins post maximal as measured by the Biosen.

Changes in the respiratory exchange ratio

时间窗: Following each 3-week supplementation period of either chlorella or placebo

Assessing the possible changes in the respiratory exchange ratio at 60% Gas Exchange threshold (GET), 80% GET, and 75% change as measured by a metabolic cart (Vyntus)

Changes in glucose

时间窗: Following each 3-week supplementation period of either chlorella or placebo

Assessing the possible changes in blood glucose at 60% Gas Exchange threshold (GET), 80% GET, and 75% change, at maximal oxygen uptake, and 15-mins post maximal as measured by the Biosen.

Changes in maximal oxygen uptake

时间窗: Following each 3-week supplementation period of either chlorella or placebo

Changes in cardiovascular fitness variables as measured by a Cardio Pulmonary Exercise Test following the submaximal run.

Changes in heart rate

时间窗: Following each 3-week supplementation period of either chlorella or placebo

Assessing the possible changes in heart rate (bpm) at 60% Gas Exchange threshold (GET), 80% GET, and 75% change as measured by a metabolic cart (Vyntus)

次要结局

  • Changes in nutritional status(Following each 3-week supplementation period of either chlorella or placebo)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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