Effectiveness of neural mobilization on pain severity, range and physical performance in individual with knee osteoarthritis

Knee osteoarthritis (Grade I–II) is a common degenerative musculoskeletal condition associated with pain, stiffness, and functional limitations. This experimental study aims to evaluate the effectiveness of passive neural mobilization on pain, physical performance, and range of motion in individuals with knee osteoarthritis presenting with non-radiating knee pain. Participants will be recruited from the physiotherapy outpatient department based on inclusion criteria. After obtaining informed consent, baseline demographic and clinical data, including age, body mass index (BMI), range of motion, and physical performance, will be recorded. Special tests such as the Prone Knee Bend Test and Straight Leg Raise (SLR) will be performed.

Participants will be allocated into an intervention group and a control group. The intervention group will receive therapist-administered passive neural mobilization techniques targeting the femoral nerve and sciatic nerve. Femoral nerve mobilization will be performed in the prone position using passive knee flexion, and sciatic nerve mobilization will be performed in the supine position using passive straight leg raise with knee extension and ankle dorsiflexion. Each technique will be applied within the pain-free range for 10–15 repetitions. The control group will receive conventional physiotherapy management as advised by the orthopedic physician.

The intervention will be carried out for six days. Outcome measures will include pain intensity assessed using the Visual Analog Scale (VAS), physical performance assessed by the 6-Minute Walk Test, and knee range of motion. Assessments will be conducted on Day 1 and Day 6 of the intervention period.