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临床试验/NCT05869370
NCT05869370招募中不适用

The Effects Of Low Intensity Training With Blood Flow Restriction In The Lower And Upper Limbs On Muscle Strength, Muscle Mass, Biochemical Parameters And Markers Of Systemic Inflammation In Rheumatoid Arthritis Patients: A Randomized Clinical Trial

Federal University of Rio Grande do Sul1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2018年5月20日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
28
试验地点
1
主要终点
Muscle strength

研究概览

简要总结

Rheumatoid arthritis (RA) patients showed systemic manifestations that may lead to a reduction in muscle strength, muscle mass and, consequently, to a reduction in physical function. On the other hand, high intensity resistance training (HIRT) are able to improve muscle strength and muscle mass in RA without affecting the disease course. However, due to the articular manifestations caused by this disease, these patients may present intolerance to HIRT. Thus, the low intensity resistance training with blood flow restriction (TBFR) may be a new training strategy for these populations. In this sense, the investigators speculate that TBFR could be beneficial in RA patients, as well as, HIRT.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
45 Years 至 65 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Rheumatoid arthritis patients;
  • All individuals will undergo an ergospirometry to ensure cardiorespiratory conditions.

排除标准

  • Fibromyalgia;
  • Cardiovascular disease;

结局指标

主要结局

Muscle strength

时间窗: Twelve weeks

1 maximum repetition test.

次要结局

未报告次要终点

研究者

发起方
Federal University of Rio Grande do Sul
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ricardo Machado Xavier

PhD

Federal University of Rio Grande do Sul

研究点 (1)

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