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临床试验/NCT07604428
NCT07604428已完成不适用

Intraocular Pressure Changes During Dry Static Apnea in Breath-Hold Divers

University Hospital Olomouc1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2018年1月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40
试验地点
1

研究概览

简要总结

This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers. Forty participants performed voluntary breath-holds while intraocular pressure, peripheral oxygen saturation (SpO2), heart rate, and blood pressure were measured at baseline, during apnea, and after apnea. The aim was to assess the magnitude and dynamics of IOP changes and their relationship to physiological parameters.

详细描述

Breath-hold diving is associated with marked physiological changes, including hypoxemia, hypercapnia, bradycardia, and increases in blood pressure. The effect of prolonged breath-holding on intraocular pressure (IOP) remains insufficiently understood.

This prospective observational study investigated changes in intraocular pressure during dry static apnea (STA) in adult breath-hold divers. Participants performed breath-holds in a supine position after a standardized resting period.

Intraocular pressure was measured using a rebound tonometer (Icare Pro, Icare Finland Oy, Helsinki, Finland). Blood pressure was measured using an automated sphygmomanometer (Omron M6 Comfort, Omron Healthcare, Kyoto, Japan). Peripheral oxygen saturation and heart rate were continuously monitored using a pulse oximeter (Beurer PO 80, Beurer Healthcare, Germany).

Measurements were obtained at baseline, during apnea and after resumption of breathing.

The primary objective was to quantify changes in intraocular pressure during STA. Secondary objectives included assessment of physiological responses and analysis of their relationship with IOP changes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age over 18 years
  • breath-hold divers at the amateur or professional level
  • signed informed consent

排除标准

  • known intraocular hypertension or glaucoma
  • refractive error > ±5.00 D
  • history of an eye injury
  • previous surgery for cataract, strabismus, or pars plana vitrectomy
  • corneal disease
  • acute eye infection

研究者

发起方
University Hospital Olomouc
申办方类型
Other
责任方
Sponsor

研究点 (1)

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