NCT02916069Unknown不适用
The Impact Multi Modal Brain Monitoring on Patient Out Come After Adult Cardiac Surgery
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 1,200
- 试验地点
- 2
- 主要终点
- S100 protein
研究概览
简要总结
Multimodal brain monitoring is feasible and can be used in formulating therapeutic strategies during cardiac surgery. Such monitoring may help to improve patient outcome and to reduce costs after cardiac surgery with CPB.
详细描述
The aim of this study is to use a combination of brain monitoring {Nearinfrared Spectroscopy (NIRS), Transcranial Doppler (TCD), bispectral index (BIS)} to formulate therapeutic strategies based on these monitors and to evaluate the impact on patient outcome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective cardiac surgery with cardiopulmonary bypass
- •Valve replacement
- •Coronary artery bypass
排除标准
- •Emergency surgery
- •Renal impairment
- •Diabetes Mellitus
结局指标
主要结局
S100 protein
时间窗: up to 24 hours
S100 protein (marker of brain injury)
次要结局
- Major neurological out come as stoke(up to 30 days after surgery)
- Mini-mental state examination(up to 30 days after surgery)
- Duration of mechanical ventilation(up to 30 days after surgery)
- Hospital stay(up to 30 days after surgery)
- Western perioperative neurological scale(up to 30 days after surgery)
研究者
Dr Mohamed Shaaban Ali, PhD, MD
Associate Professor (Anesthesiology and Critical Care)- College of Medicine-Assiut University
Assiut University
研究点 (2)
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