The Effect of Transcranial Direct-current Stimulation on Discourse Production in Healthy Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 2
- 主要终点
- Change in percent of Correct Information Units
研究概览
简要总结
The use of non-invasive brain stimulation techniques like transcranial direct-current stimulation (tDCS) for rehabilitation of language is a growing field that needs further studies to determine how best it can be used to enhance treatment outcomes. It has been shown that tDCS can improve language performance in healthy and brain-injured individuals such as increased naming accuracy.
However, at present, it is not known what effect tDCS has on higher-level language skills like discourse production (i.e. story telling, giving instructions) in healthy, older speakers. Therefore, the aim of this study is to investigate in healthy older adults, the effect of tDCS on discourse production as well as the ideal tDCS electrode placement for improving language at the discourse level. It is hypothesised that tDCS will result in greater language changes and improvements during discourse production compared to no stimulation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •At least 65 years of age
- •Native English speakers
- •Right handed
- •Normal aided or unaided visual acuity
- •At least secondary school level of education
排除标准
- •History of neurological disease or cognitive impairment
- •Any contraindication of tDCS (i.e. history of seizures, metal implants)
结局指标
主要结局
Change in percent of Correct Information Units
时间窗: pre-intervention and immediately after the intervention
The percent of accurately produced words that provide information relevant to the language task
Change in word total
时间窗: pre-intervention and immediately after the intervention
total number of words in a language sample
Change in utterance total
时间窗: pre-intervention and immediately after the intervention
total number of utterances (complete sentences including a predicate and argument) in a language sample
Change in verb total
时间窗: pre-intervention and immediately after the intervention
total number of verbs in a language sample
次要结局
- Hospital Anxiety and Depression Scale (HADS)(7 days)
- EPIC Physical Activity Questionnaire (EPAQ2)(12 months)
- The Keele Assessment of Participation (KAP)(4 weeks)