Neutrophil-to-Lymphocyte Ratio and Mortality After Emergency Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 851
- 试验地点
- 1
- 主要终点
- NLR
研究概览
简要总结
In the immune system, it has been observed that the preoperative neutrophil-to-lymphocyte ratio (NLR) is an index that reflects the state of inflammation and oxidative stress. In the perioperative period, NLR has been described as a predictor for patients who will develop renal injury, ischemic stroke, and myocardial injury. Since preoperative inflammation is a predictor of morbidity and mortality in patients undergoing non-cardiac surgery, a retrospective analysis of the inflammatory status of patients undergoing surgery at the center is proposed.
详细描述
A retrospective analysis of patients operated on at the Clinical Hospital of the University of Chile is proposed. The search will be conducted in the electronic medical records of all patients operated on between January and December 2021, with no exclusion criteria for this analysis. Demographic data, complications, length of hospital stay, and specific characteristics such as the need for mechanical ventilation, time spent in intermediate care units, and ICU as well as total hospitalization time will be recorded. For the purpose of this study, the preoperative complete blood count of the patients will be analyzed to search for hematological variables that reflect the state of preoperative systemic inflammation.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Availability of complete blood count in electronic medical records of all patients operated on between January and December 2021
排除标准
- 未提供
结局指标
主要结局
NLR
时间窗: Day of surgery
Preoperative neutrophil-to-lymphocyte ratio
Mortality
时间窗: 6 months after surgery
30 and 180 days mortality
次要结局
未报告次要终点