Utilization of Immersive Virtual Reality in Computerized Script Training for People with Aphasia: a Feasibility Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- Percentage correct in reading aloud the sentences included in the trained scripts
研究概览
简要总结
The goal of this intervention study is to investigate the effects of immersive virtual reality in rehabilitation of language and communication of individuals with post-stroke aphasia. The main research questions are:
- Is VR-based script training a feasible treatment to Cantonese-speaking PWA?
- Will VR-based script training, when compared to conventional script training, better enhance treatment outcomes in functional communication of PWA?
Participants will be assessed before, in the middle of, immediately after treatment and 8-week post treatment in terms of their performance on:
- Accuracy and time for producing trained scripts.
- Accuracy and time for producing un-trained scripts
- Standardized aphasia test on severity of language impairment
- Standardized aphasia test on functional communication
The participants will be randomly allocated to receive one of the treatment:
- Virtual reality-based computerized script training; or
- Computerized script training without virtual reality Researchers will compare the treatment outcomes of the two treatment conditions and see if treatment with virtual reality would better promote outcomes when compared to training without virtual reality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
- •premorbid fluent Cantonese speakers,
- •aged between 30 and 80 years,
- •no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
- •no motor speech disorders of moderate to severe level, and
- •normal or corrected-to-normal vision and hearing functions
排除标准
- •concurrent participation in other aphasia treatment trials, and
- •incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.
结局指标
主要结局
Percentage correct in reading aloud the sentences included in the trained scripts
时间窗: From baseline up to 1-week post training
Trained scripts will be shown in written form while the PWA will be asked to read aloud the scripts.
Time required in read aloud of trained scripts
时间窗: From baseline up to 1-week post training
Total time to read aloud the trained scripts
Percentage correct in spontaneous production of the sentences included in the trained scripts
时间窗: From baseline up to 1-week post training
No written cue will be provided while the PWA will produce the scripts upon questions.
Time required for spantaneous production of trained scripts
时间窗: From baseline up to 1-week post training
No written cue will be provided while the PWA will produce the scripts upon questions.
次要结局
- CAB(From baseline up to 1-week post training)
- Percentage correct in producing untrained but related scripts(From baseline up to 1-week post training)
- CANELT(From baseline up to 1-week post training)