Is Entamoeba Gingivalis A Risk Factor In Periodontal Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Presence of Entamoaba Gingivalis parasite in dental plaque assessed by direct microscopic examination
研究概览
简要总结
This current study aims to clarify the relationship between the occurrence of Entamoeba gingivalis infection and the specter of gingivitis & chronic periodontitis among Egyptian patients in comparison to healthy volunteers as a control group.
详细描述
Three groups will be included in the current study. 40 Plaque samples will be collected from gingivitis patients (group 1), 40 from chronic periodontitis patients (group 2) plus 40 samples from healthy volunteers (group 3). Diagnosis of parasitic stages will rely on direct microscopic detection using permanent stains, Trichrome stain and haematoxylin and eosin stain in addition to direct wet mount examination.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 35 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Chronic Gingivitis patients with signs of clinical inflammation with no clinical attachment loss.
- •Chronic Periodontitis patients having probing depth of ≥3 mm and clinical attachment level ≥ 1 mm.
- •The control group: healthy subjects who attend the restorative dental clinic and had clinically healthy gingiva.
排除标准
- •Patients with any systemic diseases
结局指标
主要结局
Presence of Entamoaba Gingivalis parasite in dental plaque assessed by direct microscopic examination
时间窗: 2 weeks
Direct microscopic detection of Entamoaba Gingivalis in dental plaque samples using Trichrome stain
次要结局
未报告次要终点
研究者
Gihane Gharib Madkour
Associate Professor
Cairo University