Pharmacokinetic, Thermogenic, Hemodynamic, Ergogenic Assessment of a Pre-Workout Dietary Supplement
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Optimize nutrient delivery prior to exercise by assessing Readiness to Perform Visual Analog Scale.
研究概览
简要总结
The purpose of this study is to examine the acute effects of a pre-workout dietary supplement on energy metabolism, cardiovascular hemodynamics, blood metabolites and mental focus.
详细描述
A number of nutritional strategies have been developed to optimize nutrient delivery prior to exercise. This includes providing carbohydrate and a number of ergogenic nutrients prior to, during and/or following exercise. As a result a number of pre-workout supplements have been developed to increase energy availability, promote vasodilation and/or positively affect exercise capacity. The purpose of this study is to investigate the potential ergogenic value of acute ingestion of a pre-workout dietary supplement prior to exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •you are an apparently healthy and recreationally active man or woman between the ages of 18 and 40;
- •you will need to have at least six months immediate prior history of resistance training on the bench press and leg press or squat;
排除标准
- •you have a history of treatment for metabolic disease (i.e., diabetes), hypertension, hypo-tension, thyroid disease, arrhythmia and/or cardiovascular disease;
- •you are currently using prescription medications;
- •you have an intolerance to caffeine and/or other natural stimulants;
- •you are pregnant or a lactating female or plan to become pregnant with the next month;
- •you have a history of smoking;
- •you drink excessively (i.e., 12 drinks per week or more);
研究组 & 干预措施
C4 Extreme
One dose of 12 grams (powder mixed with water): 1500 mg beta alanine, 1000 mg creatine nitrate, 1000 mg arginine AKG, 250 mg vitamin C, 150 mg n-acetyle tyrosine, 135 mg caffeine, 7.5 mg l-dopa, 30 mg vitamin B3, 10 mg synephrine, 0.5 mg vitamin B6, 0.25 mg vitamin B9, 0.035 mg vitamin B12.
干预措施: C4 Extreme (Dietary Supplement)
C4 Extreme (without Advantra Z)
One dose of 12 grams (powder mixed with water): 1500 mg beta alanine, 1000 mg creatine nitrate, 1000 mg arginine AKG, 250 mg vitamin C, 150 mg n-acetyle tyrosine, 135 mg caffeine, 7.5 mg l-dopa, 30 mg vitamin B3, 0.5 mg vitamin B6, 0.25 mg vitamin B9, 0.035 mg vitamin B12.
干预措施: C4 Extreme (without Advantra Z (Dietary Supplement)
Placebo
One dose of flavored placebo (powder mixed with water)
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Optimize nutrient delivery prior to exercise by assessing Readiness to Perform Visual Analog Scale.
时间窗: Three weeks
Optimize nutrient delivery prior to exercise by assessing Blood Pressure.
时间窗: Three weeks
Optimize nutrient delivery prior to exercise by assessing; cognitive function (i.e., Stroop Color and Word Test and Word Recall Test).
时间窗: Three weeks
Optimize nutrient delivery prior to exercise by assessing Resting Energy Expenditure.
时间窗: Three weeks
Optimize nutrient delivery prior to exercise by assessing Heart Rate.
时间窗: Three weeks
Optimize nutrient delivery prior to exercise by assessing ECG.
时间窗: Three weeks
次要结局
- Measure Heart Rate to evaluate safety.(Three weeks)
- Measure Blood Pressure to evaluate safety.(Three weeks)
- Measure standard clinical chemistry panels in the blood to evaluate safety.(Three weeks)
- Measure ECG to evaluate safety.(Three weeks)