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临床试验/NCT07627152
NCT07627152已完成不适用

Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial

Istanbul Nisantasi University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年4月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40
试验地点
1
主要终点
Pain Intensity

研究概览

简要总结

The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults.

The main questions it aims to answer are:

  • Does isometric exercise reduce pain associated with delayed onset muscle soreness?
  • Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness?

Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS.

Participants will:

  • Undergo a standardized exercise protocol to induce delayed onset muscle soreness.
  • Be randomly assigned to either an isometric exercise group or a control group.
  • Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference.
  • Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.

详细描述

Delayed onset muscle soreness (DOMS) is a common consequence of unaccustomed or high-intensity physical activity, particularly exercises involving eccentric muscle contractions. DOMS is characterized by pain, tenderness, temporary reductions in muscle function, decreased range of motion, and impaired physical performance, typically peaking between 24 and 72 hours after exercise.

Various recovery strategies have been investigated to reduce the symptoms of DOMS; however, evidence regarding the effectiveness of isometric exercise in facilitating recovery remains limited. Previous studies have suggested that isometric muscle contractions may induce analgesic effects and increase pressure pain thresholds in musculoskeletal conditions. Whether these effects can improve recovery following exercise-induced muscle damage and DOMS has not been fully established.

The purpose of this randomized controlled trial was to investigate the effects of an isometric exercise program on recovery following experimentally induced DOMS in healthy adults. DOMS was induced using a standardized drop-jump protocol. Participants were randomly assigned to either an isometric exercise group or a control group. Outcome assessments were performed before DOMS induction, immediately after exercise, and during follow-up evaluations on Days 1, 3, and 5.

The findings of this study may contribute to the understanding of the role of isometric exercise as a simple, low-cost, and clinically applicable recovery strategy following exercise-induced muscle soreness.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Active athletes competing in University sports teams.
  • Age between 18 and 30 years.
  • Participation in organized sports training at least three times per week for the previous six months.
  • No lower-extremity pain at the time of enrollment.
  • Ability to safely perform the exercise protocol used to induce delayed onset muscle soreness (DOMS).
  • Willingness to provide written informed consent.

排除标准

  • History of lower-extremity musculoskeletal injury within the previous 6 months.
  • Previous lower-extremity surgery.
  • Current musculoskeletal pain or injury affecting sports participation.
  • Neurological, rheumatological, cardiovascular, or systemic disorders affecting physical performance.
  • Use of analgesic, anti-inflammatory, or muscle-relaxant medications during the study period.
  • Participation in strenuous eccentric exercise within 72 hours prior to baseline testing.
  • Use of recovery interventions (e.g., massage, cryotherapy, compression garments, electrical stimulation) during the study period.
  • Inability to complete the exercise protocol or follow-up assessments.

研究组 & 干预措施

Isometric Exercise Group

Experimental

Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.

干预措施: Isometric Exercise (Other)

Sham Exercise Group

Sham Comparator

Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.

干预措施: Sham Exercise (Other)

结局指标

主要结局

Pain Intensity

时间窗: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

Pain intensity will be assessed using the Visual Analog Scale (VAS). The VAS consists of a 10-cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will indicate their perceived pain intensity by marking a point on the line. Higher scores indicate greater pain intensity.

次要结局

未报告次要终点

研究者

发起方
Istanbul Nisantasi University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Onur Atakan Sekibağ

Principal investigator

Istanbul Nisantasi University

研究点 (1)

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