Effect of Circadian Timing of a Standardized Meal on Postprandial Glucose Response in Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Incremental Area Under the Curve (iAUC) for Postprandial Glucose
研究概览
简要总结
This randomized crossover study aims to investigate the effect of circadian timing of a standardized meal (morning versus evening consumption) on postprandial glucose response in healthy adults. Postprandial glucose will be assessed using the incremental area under the curve (iAUC) over 120 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged 18 years and older
- •Able and willing to provide informed consent
- •Able to comply with study procedures
排除标准
- •Diagnosis of diabetes or any metabolic disorder affecting glucose regulation
- •Use of any medications
- •Pregnant or breastfeeding women
- •Night shift workers or individuals with irregular sleep patterns
研究组 & 干预措施
Morning Meal Condition
Participants will consume a standardized test meal in the morning following an overnight fasting period of at least 8 hours. Postprandial glucose will be measured over 120 minutes.
干预措施: Standardized Test Meal (Other)
Evening Meal Condition
Participants will consume the same standardized test meal in the evening following a standardized fasting period of at least 8 hours prior to the test meal. Postprandial glucose will be measured over 120 minutes.
干预措施: Standardized Test Meal (Other)
结局指标
主要结局
Incremental Area Under the Curve (iAUC) for Postprandial Glucose
时间窗: Baseline to 120 minutes after consumption of the standardized test meal
The primary objective of this study is to investigate the effect of circadian timing of a standardized test meal (morning versus evening consumption) on postprandial glucose response in healthy adults, assessed as the incremental area under the curve (iAUC) for capillary blood glucose over 120 minutes following meal consumption
次要结局
- Peak Postprandial Glucose (Morning vs Evening)(Baseline to 120 minutes after consumption of the standardized test meal)
- Time to Peak Glucose (Morning vs Evening)(Baseline to 120 minutes after consumption of the standardized test meal)
- Postprandial Glucose Profile (Morning vs Evening)(Baseline, 15, 30, 60, 90, and 120 minutes after consumption of the standardized test meal)